Anthropometric, Cardiopulmonary and Metabolic Benefits of the High-Intensity Interval Training Versus Moderate, Low-Intensity or Control for Type 2 Diabetes: Systematic Review and Meta-Analysis

Abstract: This study aims to evaluate the effectiveness of high-intensity interval training compared with no intervention and other types of training interventions for people with Type 2 Diabetes. A systematic review and meta-analysis of randomized controlled trials that used high-interval intensity training to improve anthropometric, cardiopulmonary and metabolic conditions were conducted. The search was performed during October-December 2017 using the databases PubMed, Web of Science and Physiotherapy Evidence Database (PEDro). The methodological quality of the studies was evaluated using the PEDro scale. A total of 10 articles were included in this meta-analysis. After statistical analysis, favorable results were obtained for high-Intensity Interval Training compared with control (non-intervention): [Weight: Standardized mean difference (SMD) = -2.09; confidence interval (CI) 95%: (-3.41; -0.78); body-mass index: SMD = -3.73; CI 95%: (-5.53; -1.93); systolic blood pressure: SMD = -4.55; CI 95%: (-8.44; -0.65); VO_2max: SMD = 12.20; CI 95%: (0.26; 24.14); HbA_1c: SMD = -3.72; CI 95%: (-7.34; -0.10)], moderate intensity continuous training: [body-mass index: SMD = -0.41; CI 95%: (-0.80; -0.03); VO_2max: SMD = 1.91; CI 95%: (0.18; 3.64)], and low intensity training: [Weight: SMD = -2.06; CI 95%: (-2.80; -1.31); body-mass index: SMD = -3.04; CI 95%: (-5.16; -0.92); systolic blood pressure: SMD = -2.17; CI 95%: (-3.93; -0.41); HbA_1c: SMD = -1.58; CI 95%: (-1.84; -1.33)]. The results show that high-intensity interval training can be a useful strategy in order to improve anthropometric, cardiopulmonary and metabolic parameters in people with Type 2 diabetes. Despite this, it could be essential to clarify and unify criteria in the intervention protocols, being necessary new lines of research.