Michael additions of amines to methyl acrylates promoted by microwave irradiation

Molecules. 2008 Feb 7;13(2):340-7. doi: 10.3390/molecules13020340.

Abstract

A simple and efficient protocol has been developed for the Michael addition of amines to alpha,beta-unsaturated esters under microwave irradiation. Under these conditions there was a significant decrease in the reaction time, increases in the yields and increased purity of the products.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylates / chemistry*
  • Amines / chemistry*
  • Benzylamines / chemistry
  • Esters / chemical synthesis
  • Esters / chemistry
  • Microwaves*
  • Models, Chemical*

Substances

  • Acrylates
  • Amines
  • Benzylamines
  • Esters
  • methyl acrylate