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TRPV1 activation power can switch an action mode for its polypeptide ligands.
Nikolaev MV, Dorofeeva NA, Komarova MS, Korolkova YV, Andreev YA, Mosharova IV, Grishin EV, Tikhonov DB, Kozlov SA. Nikolaev MV, et al. Among authors: mosharova iv. PLoS One. 2017 May 5;12(5):e0177077. doi: 10.1371/journal.pone.0177077. eCollection 2017. PLoS One. 2017. PMID: 28475608 Free PMC article.
New Disulfide-Stabilized Fold Provides Sea Anemone Peptide to Exhibit Both Antimicrobial and TRPA1 Potentiating Properties.
Logashina YA, Solstad RG, Mineev KS, Korolkova YV, Mosharova IV, Dyachenko IA, Palikov VA, Palikova YA, Murashev AN, Arseniev AS, Kozlov SA, Stensvåg K, Haug T, Andreev YA. Logashina YA, et al. Among authors: mosharova iv. Toxins (Basel). 2017 Apr 29;9(5):154. doi: 10.3390/toxins9050154. Toxins (Basel). 2017. PMID: 28468269 Free PMC article.
Probing temperature and capsaicin-induced activation of TRPV1 channel via computationally guided point mutations in its pore and TRP domains.
Lubova KI, Chugunov AO, Volynsky PE, Trofimov Y, Korolkova YV, Mosharova IV, Kozlov SA, Andreev YA, Efremov RG. Lubova KI, et al. Among authors: mosharova iv. Int J Biol Macromol. 2020 May 1:S0141-8130(20)33110-X. doi: 10.1016/j.ijbiomac.2020.04.239. Online ahead of print. Int J Biol Macromol. 2020. PMID: 32371130
Peptide from Sea Anemone Metridium senile Affects Transient Receptor Potential Ankyrin-repeat 1 (TRPA1) Function and Produces Analgesic Effect.
Logashina YA, Mosharova IV, Korolkova YV, Shelukhina IV, Dyachenko IA, Palikov VA, Palikova YA, Murashev AN, Kozlov SA, Stensvåg K, Andreev YA. Logashina YA, et al. Among authors: mosharova iv. J Biol Chem. 2017 Feb 17;292(7):2992-3004. doi: 10.1074/jbc.M116.757369. Epub 2017 Jan 11. J Biol Chem. 2017. PMID: 28077580 Free PMC article.