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Showing results for ioannis domains
Your search for Ioannis Doumanis retrieved no results
A membrane-associated MHC-I inhibitory axis for cancer immune evasion.
Chen X, Lu Q, Zhou H, Liu J, Nadorp B, Lasry A, Sun Z, Lai B, Rona G, Zhang J, Cammer M, Wang K, Al-Santli W, Ciantra Z, Guo Q, You J, Sengupta D, Boukhris A, Zhang H, Liu C, Cresswell P, Dahia PLM, Pagano M, Aifantis I, Wang J. Chen X, et al. Cell. 2023 Aug 31;186(18):3903-3920.e21. doi: 10.1016/j.cell.2023.07.016. Epub 2023 Aug 8. Cell. 2023. PMID: 37557169 Free PMC article.
To map such mechanisms of resistance, we identified key MHC-I regulators using specific peptide-MHC-I-guided CRISPR-Cas9 screens in AML. The top-ranked negative regulators were surface protein sushi domain containing 6 (SUSD6), transmembrane protein 127 (TMEM …
To map such mechanisms of resistance, we identified key MHC-I regulators using specific peptide-MHC-I-guided CRISPR-Cas9 screens in AML. The …
Genetic Pathways in Peritoneal Mesothelioma Tumorigenesis.
Panagopoulos I, Andersen K, Brunetti M, Gorunova L, Davidson B, Lund-Iversen M, Micci F, Heim S. Panagopoulos I, et al. Cancer Genomics Proteomics. 2023 Jul-Aug;20(4):363-374. doi: 10.21873/cgp.20388. Cancer Genomics Proteomics. 2023. PMID: 37400148 Free PMC article.
OMERACT 2023 Systemic Lupus Erythematosus Special Interest Group: Winnowing and Binning Preliminary Candidate Domains for the Core Outcome Set.
Nielsen W, Strand V, Simon LS, Parodis I, Kim AHJ, Desai M, Enman Y, Wallace D, Chaichian Y, Navarra S, Aranow C, MacKay M, Trotter K, Tayer-Shifman OE, Duarte-Garcia A, Shan Tam L, Ugarte-Gil MF, PonsEstel GJ, Reynolds JA, Nikpour M, Hoi A, Romero-Diaz J, Papachristos D, Aggarwal A, Mok CC, Fujio K, Ramsey-Goldman R, Howe A, Kia BN, Bonilla D, Thumboo J, Mosca M, Aringer M, Johnson SR, Drucker AM, Morand E, Bruce I, Touma Z; OMERACT SLE Working Group. Nielsen W, et al. Semin Arthritis Rheum. 2024 Apr;65:152380. doi: 10.1016/j.semarthrit.2024.152380. Epub 2024 Jan 14. Semin Arthritis Rheum. 2024. PMID: 38281467
OBJECTIVE: The objective of the SIG and the subsequent meetings of the SLE Working Group was to begin the winnowing and binning of candidate domain sub-themes into a preliminary list of candidate domains that will proceed to the consensus Delphi exercise for the SLE …
OBJECTIVE: The objective of the SIG and the subsequent meetings of the SLE Working Group was to begin the winnowing and binning of candidate …
Nonalcoholic fatty liver disease: lifestyle and quality of life.
Vachliotis I, Goulas A, Papaioannidou P, Polyzos SA. Vachliotis I, et al. Hormones (Athens). 2022 Mar;21(1):41-49. doi: 10.1007/s42000-021-00339-6. Epub 2021 Dec 1. Hormones (Athens). 2022. PMID: 34854066 Review.
Apart from being affected by lifestyle, NAFLD may also affect patients' quality of life (QoL), mostly in the domain of physical function. In this regard, while the early and more benign form of the disease, i.e., simple hepatic steatosis, may not affect QoL, there is evide …
Apart from being affected by lifestyle, NAFLD may also affect patients' quality of life (QoL), mostly in the domain of physical funct …
The current and future uses of machine learning in ecosystem service research.
Scowen M, Athanasiadis IN, Bullock JM, Eigenbrod F, Willcock S. Scowen M, et al. Sci Total Environ. 2021 Dec 10;799:149263. doi: 10.1016/j.scitotenv.2021.149263. Epub 2021 Jul 27. Sci Total Environ. 2021. PMID: 34426354 Free article. Review.
Descriptive ML techniques group data with little or no prior domain specific assumptions; they can generate hypotheses and automatically sort data prior to other analyses. ...
Descriptive ML techniques group data with little or no prior domain specific assumptions; they can generate hypotheses and automatica …
Detection and genomic analysis of BRAF fusions in Juvenile Pilocytic Astrocytoma through the combination and integration of multi-omic data.
Zwaig M, Baguette A, Hu B, Johnston M, Lakkis H, Nakada EM, Faury D, Juretic N, Ellezam B, Weil AG, Karamchandani J, Majewski J, Blanchette M, Taylor MD, Gallo M, Kleinman CL, Jabado N, Ragoussis J. Zwaig M, et al. BMC Cancer. 2022 Dec 12;22(1):1297. doi: 10.1186/s12885-022-10359-z. BMC Cancer. 2022. PMID: 36503484 Free PMC article.
BACKGROUND: Juvenile Pilocytic Astrocytomas (JPAs) are one of the most common pediatric brain tumors, and they are driven by aberrant activation of the mitogen-activated protein kinase (MAPK) signaling pathway. RAF-fusions are the most common genetic alterations identified …
BACKGROUND: Juvenile Pilocytic Astrocytomas (JPAs) are one of the most common pediatric brain tumors, and they are driven by aberrant activa …
Efficacy of lifestyle interventions in the management of systemic lupus erythematosus: a systematic review of the literature.
Tsoi A, Gomez A, Boström C, Pezzella D, Chow JW, Girard-Guyonvarc'h C, Stamm T, Arnaud L, Parodis I. Tsoi A, et al. Rheumatol Int. 2024 May;44(5):765-778. doi: 10.1007/s00296-024-05548-x. Epub 2024 Mar 7. Rheumatol Int. 2024. PMID: 38451302 Free PMC article.
Overall, the quality of the evidence is limited, and there were multiple sources of heterogeneity. The two domains most extensively researched were mental health (40 records) and physical exercise (39 records). ...
Overall, the quality of the evidence is limited, and there were multiple sources of heterogeneity. The two domains most extensively r …
Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Kantsadi AL, Hatzopoulos GN, Gönczy P, Vakonakis I. Kantsadi AL, et al. Structure. 2022 May 5;30(5):671-684.e5. doi: 10.1016/j.str.2022.02.005. Epub 2022 Mar 2. Structure. 2022. PMID: 35240058 Free PMC article.
Centrioles have proximal-distal polarity and a 9-fold radial symmetry imparted by a likewise symmetrical central scaffold, the cartwheel. The spindle assembly abnormal protein 6 (SAS-6) self-assembles into 9-fold radially symmetric ring-shaped oligomers that stack via an u …
Centrioles have proximal-distal polarity and a 9-fold radial symmetry imparted by a likewise symmetrical central scaffold, the cartwheel. Th …
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia.
Kloetgen A, Thandapani P, Ntziachristos P, Ghebrechristos Y, Nomikou S, Lazaris C, Chen X, Hu H, Bakogianni S, Wang J, Fu Y, Boccalatte F, Zhong H, Paietta E, Trimarchi T, Zhu Y, Van Vlierberghe P, Inghirami GG, Lionnet T, Aifantis I, Tsirigos A. Kloetgen A, et al. Nat Genet. 2020 Apr;52(4):388-400. doi: 10.1038/s41588-020-0602-9. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203470 Free PMC article.
Differences in three-dimensional (3D) chromatin architecture can influence the integrity of topologically associating domains (TADs) and rewire specific enhancer-promoter interactions, impacting gene expression and leading to human disease. ...
Differences in three-dimensional (3D) chromatin architecture can influence the integrity of topologically associating domains (TADs) …
The miR-199a/214 Cluster Controls Nephrogenesis and Vascularization in a Human Embryonic Stem Cell Model.
Bantounas I, Lopes FM, Rooney KM, Woolf AS, Kimber SJ. Bantounas I, et al. Stem Cell Reports. 2021 Jan 12;16(1):134-148. doi: 10.1016/j.stemcr.2020.11.007. Epub 2020 Dec 10. Stem Cell Reports. 2021. PMID: 33306987 Free PMC article.
After confirming expression in each model, we inhibited the miRNAs using lentivirally transduced miRNA sponges. This reduced the WT1(+) metanephric mesenchyme domain in 2D cultures. Sponges did not prevent the formation of 3D kidney-like organoids. ...
After confirming expression in each model, we inhibited the miRNAs using lentivirally transduced miRNA sponges. This reduced the WT1(+) meta …
59 results