Biomimetic Synthesis of an Antiviral Cinnamoylphloroglucinol Collection from Cleistocalyx operculatus: A Synthetic Strategy Based on Biogenetic Building Blocks.
Wang J, Song JG, Zhong DL, Duan ZZ, Peng ZJ, Tang W, Song QY, Huang XJ, Hu LJ, Wang Y, Ye WC.
Wang J, et al.
Angew Chem Int Ed Engl. 2023 Dec 11;62(50):e202312568. doi: 10.1002/anie.202312568. Epub 2023 Nov 9.
Angew Chem Int Ed Engl. 2023.
PMID: 37848394
These syntheses proceeded successfully in only six to seven steps starting from commercially available 1,3,5-benzenetriol and involving oxidative activation of stable biogenetic building blocks as a crucial step. Key features of the syntheses include a unique Michael addit …
These syntheses proceeded successfully in only six to seven steps starting from commercially available 1,3,5-benzenetriol and involving oxid …