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Human milk inhibits some enveloped virus infections, including SARS-CoV-2, in an intestinal model.
Aknouch I, Sridhar A, Freeze E, Giugliano FP, van Keulen BJ, Romijn M, Calitz C, García-Rodríguez I, Mulder L, Wildenberg ME, Muncan V, van Gils MJ, van Goudoever JB, Stittelaar KJ, Wolthers KC, Pajkrt D. Aknouch I, et al. Among authors: garcia rodriguez i. Life Sci Alliance. 2022 Aug 4;5(12):e202201432. doi: 10.26508/lsa.202201432. Life Sci Alliance. 2022. PMID: 35926873 Free PMC article.
Amino acid variation at VP1-145 of enterovirus A71 determines the viral infectivity and receptor usage in a primary human intestinal model.
Aknouch I, García-Rodríguez I, Giugliano FP, Calitz C, Koen G, van Eijk H, Johannessson N, Rebers S, Brouwer L, Muncan V, Stittelaar KJ, Pajkrt D, Wolthers KC, Sridhar A. Aknouch I, et al. Among authors: garcia rodriguez i. Front Microbiol. 2023 Apr 17;14:1045587. doi: 10.3389/fmicb.2023.1045587. eCollection 2023. Front Microbiol. 2023. PMID: 37138595 Free PMC article.
Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease.
Capendale PE, García-Rodríguez I, Ambikan AT, Mulder LA, Depla JA, Freeze E, Koen G, Calitz C, Sood V, Vieira de Sá R, Neogi U, Pajkrt D, Sridhar A, Wolthers KC. Capendale PE, et al. Among authors: garcia rodriguez i. Nat Commun. 2024 Mar 21;15(1):2532. doi: 10.1038/s41467-024-46634-9. Nat Commun. 2024. PMID: 38514653 Free PMC article.
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models.
García-Rodríguez I, Moreni G, Capendale PE, Mulder L, Aknouch I, Vieira de Sá R, Johannesson N, Freeze E, van Eijk H, Koen G, Wolthers KC, Pajkrt D, Sridhar A, Calitz C. García-Rodríguez I, et al. Antiviral Res. 2024 Feb;222:105798. doi: 10.1016/j.antiviral.2024.105798. Epub 2024 Jan 6. Antiviral Res. 2024. PMID: 38190972 Free article.