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Positive and negative modulation of group I metabotropic glutamate receptors.
Vanejevs M, Jatzke C, Renner S, Müller S, Hechenberger M, Bauer T, Klochkova A, Pyatkin I, Kazyulkin D, Aksenova E, Shulepin S, Timonina O, Haasis A, Gutcaits A, Parsons CG, Kauss V, Weil T. Vanejevs M, et al. Among authors: pyatkin i. J Med Chem. 2008 Feb 14;51(3):634-47. doi: 10.1021/jm0611298. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173231
Discovery, synthesis, and structure-activity relationships of 2-aminoquinazoline derivatives as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators.
Kubas H, Meyer U, Krueger B, Hechenberger M, Vanejevs M, Zemribo R, Kauss V, Ambartsumova R, Pyatkin I, Polosukhin AI, Abel U. Kubas H, et al. Among authors: pyatkin i. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4493-500. doi: 10.1016/j.bmcl.2013.06.049. Epub 2013 Jun 25. Bioorg Med Chem Lett. 2013. PMID: 23856046