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Page 1
Design, Synthesis, and Antiviral Activity of the Thiazole Positional Isomers of a Potent HIV-1 Entry Inhibitor NBD-14270.
ChemMedChem. 2022 Nov 18;17(22):e202200344. doi: 10.1002/cmdc.202200344. Epub 2022 Sep 29.
ChemMedChem. 2022.
PMID: 36097139
Design and Synthesis of Fsp3-Enriched Spirocyclic-Based Biological Screening Compound Arrays via DOS Strategies and Their NNMT Inhibition Profiling.
Iusupov IR, Lukyanenko ER, Altieri A, Kurkin AV.
Iusupov IR, et al.
ChemMedChem. 2022 Dec 16;17(24):e202200394. doi: 10.1002/cmdc.202200394. Epub 2022 Oct 27.
ChemMedChem. 2022.
PMID: 36193863
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Design of gp120 HIV-1 entry inhibitors by scaffold hopping via isosteric replacements.
Iusupov IR, Curreli F, Spiridonov EA, Markov PO, Ahmed S, Belov DS, Manasova EV, Altieri A, Kurkin AV, Debnath AK.
Iusupov IR, et al.
Eur J Med Chem. 2021 Nov 15;224:113681. doi: 10.1016/j.ejmech.2021.113681. Epub 2021 Jul 7.
Eur J Med Chem. 2021.
PMID: 34246921
Free PMC article.
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Design, synthesis, and antiviral activity of a series of CD4-mimetic small-molecule HIV-1 entry inhibitors.
Curreli F, Ahmed S, Benedict Victor SM, Iusupov IR, Spiridonov EA, Belov DS, Altieri A, Kurkin AV, Debnath AK.
Curreli F, et al. Among authors: iusupov ir.
Bioorg Med Chem. 2021 Feb 15;32:116000. doi: 10.1016/j.bmc.2021.116000. Epub 2021 Jan 8.
Bioorg Med Chem. 2021.
PMID: 33461144
Free PMC article.
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Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation.
Curreli F, Ahmed S, Benedict Victor SM, Iusupov IR, Belov DS, Markov PO, Kurkin AV, Altieri A, Debnath AK.
Curreli F, et al. Among authors: iusupov ir.
J Med Chem. 2020 Feb 27;63(4):1724-1749. doi: 10.1021/acs.jmedchem.9b02149. Epub 2020 Feb 17.
J Med Chem. 2020.
PMID: 32031803
Free PMC article.
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