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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1952 2
1953 3
1954 6
1955 3
1956 14
1957 17
1958 14
1959 2
1962 1
1963 8
1964 25
1965 13
1966 21
1967 32
1968 44
1969 28
1970 36
1971 35
1972 19
1973 18
1974 15
1975 20
1976 17
1977 25
1978 25
1979 36
1980 36
1981 68
1982 143
1983 277
1984 460
1985 725
1986 883
1987 1084
1988 1463
1989 1794
1990 1980
1991 2130
1992 2305
1993 2800
1994 2934
1995 3154
1996 3438
1997 3637
1998 4088
1999 4318
2000 4682
2001 4718
2002 4713
2003 4945
2004 5085
2005 5660
2006 5927
2007 6257
2008 6686
2009 7112
2010 7905
2011 8460
2012 8684
2013 8920
2014 9399
2015 10064
2016 9780
2017 9923
2018 9889
2019 10094
2020 10466
2021 10103
2022 6026
2023 4999
2024 1703

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200,357 results

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Page 1
Interleukin-26.
Fickenscher H, Pirzer H. Fickenscher H, et al. Int Immunopharmacol. 2004 May;4(5):609-13. doi: 10.1016/j.intimp.2004.01.004. Int Immunopharmacol. 2004. PMID: 15120646 Review.
Interleukin-26 (IL-26), initially termed AK155, is a cellular sequence homolog to IL-10 belonging to the IL-10 cytokine family. ...Moreover, the T-lymphokine IL-26 is highly likely to play a role in normal and pathological hematology or immunology …
Interleukin-26 (IL-26), initially termed AK155, is a cellular sequence homolog to IL-10 belonging to the IL-10 cytokine …
Regulation of IL-22BP in psoriasis.
Voglis S, Moos S, Kloos L, Wanke F, Zayoud M, Pelczar P, Giannou AD, Pezer S, Albers M, Luessi F, Huber S, Schäkel K, Kurschus FC. Voglis S, et al. Sci Rep. 2018 Mar 23;8(1):5085. doi: 10.1038/s41598-018-23510-3. Sci Rep. 2018. PMID: 29572462 Free PMC article.
IL-22 is a potent pro-inflammatory cytokine upregulated in psoriasis and in other inflammatory diseases. The function of IL-22 is regulated by the soluble scavenging receptor, IL-22 binding protein (IL-22BP or IL-22RA2). ...
IL-22 is a potent pro-inflammatory cytokine upregulated in psoriasis and in other inflammatory diseases. The function of IL-22 …
Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4(+) T Cells.
Lin X, Tawch S, Wong HT, Roy S, Gaudino S, Castillo P, Elsegeiny W, Wakabayashi N, Oury TD, Pociask D, Chen K, McLinskey N, Melville P, Syritsyna O, Coyle P, Good M, Awasthi A, Kolls JK, Kumar P. Lin X, et al. J Immunol. 2021 Apr 1;206(7):1540-1548. doi: 10.4049/jimmunol.1900656. Epub 2021 Mar 1. J Immunol. 2021. PMID: 33648937 Free PMC article.
In this study, we show that CDDO-Im, a specific Nrf2 activator, promotes IL-17A and IL-22 responses in murine Th17 cells. In contrast, CDDO-Im inhibits IL-17A response in multiple sclerosis patient-derived PBMCs. ...
In this study, we show that CDDO-Im, a specific Nrf2 activator, promotes IL-17A and IL-22 responses in murine Th17 cell …
Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF.
Delacher M, Imbusch CD, Hotz-Wagenblatt A, Mallm JP, Bauer K, Simon M, Riegel D, Rendeiro AF, Bittner S, Sanderink L, Pant A, Schmidleithner L, Braband KL, Echtenachter B, Fischer A, Giunchiglia V, Hoffmann P, Edinger M, Bock C, Rehli M, Brors B, Schmidl C, Feuerer M. Delacher M, et al. Immunity. 2020 Feb 18;52(2):295-312.e11. doi: 10.1016/j.immuni.2019.12.002. Epub 2020 Jan 7. Immunity. 2020. PMID: 31924477 Free PMC article.
Using transcription factor nuclear factor, interleukin 3 regulated (Nfil3) reporter mice and single-cell RNA-sequencing (scRNA-seq), we identified two precursor stages of interleukin 33 (IL-33) receptor ST2-expressing nonlymphoid tissue Treg cells, which resided in the spl …
Using transcription factor nuclear factor, interleukin 3 regulated (Nfil3) reporter mice and single-cell RNA-sequencing (scRNA-seq), we iden …
Comparison of IL-2 vs IL-7/IL-15 for the generation of NY-ESO-1-specific T cells.
Gong W, Hoffmann JM, Stock S, Wang L, Liu Y, Schubert ML, Neuber B, Hückelhoven-Krauss A, Gern U, Schmitt A, Müller-Tidow C, Shiku H, Schmitt M, Sellner L. Gong W, et al. Cancer Immunol Immunother. 2019 Jul;68(7):1195-1209. doi: 10.1007/s00262-019-02354-4. Epub 2019 Jun 8. Cancer Immunol Immunother. 2019. PMID: 31177329
IL-7/IL-15 increased the proportion of T(N). However, the absolute number of T(N) did not increase due to a significantly slower expansion of T cells with IL-7/IL-15. In conclusion, IL-7/IL-15 does not seem to be superior to IL-2 f …
IL-7/IL-15 increased the proportion of T(N). However, the absolute number of T(N) did not increase due to a significantly slow …
[Pathogenesis of psoriasis].
Schäkel K, Schön MP, Ghoreschi K. Schäkel K, et al. Hautarzt. 2016 Jun;67(6):422-31. doi: 10.1007/s00105-016-3800-8. Hautarzt. 2016. PMID: 27246016 Review. German.
The T cell response is orchestrated by CD 8(+) T cells in the epidermis and by CD 4(+) T cells in the dermis that predominantly produce interleukin-17 (IL-17). Research of the past 15 years unraveled cellular and molecular mechanisms as well as cytokines like TNF-alpha or …
The T cell response is orchestrated by CD 8(+) T cells in the epidermis and by CD 4(+) T cells in the dermis that predominantly produce inte …
IL-1beta Induces SOCS2 Expression in Human Dendritic Cells.
Sarajlic M, Neuper T, Föhrenbach Quiroz KT, Michelini S, Vetter J, Schaller S, Horejs-Hoeck J. Sarajlic M, et al. Int J Mol Sci. 2019 Nov 25;20(23):5931. doi: 10.3390/ijms20235931. Int J Mol Sci. 2019. PMID: 31775389 Free PMC article.
Thus, IL-1beta signaling must be tightly regulated. As suppressor of cytokine signaling (SOCS) proteins effectively control immune responses, we investigated the role of SOCS2 in IL-1beta-induced DC activation. ...SOCS2 expression was also analyzed in a curated NCBI …
Thus, IL-1beta signaling must be tightly regulated. As suppressor of cytokine signaling (SOCS) proteins effectively control immune re …
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses.
Gorby C, Sotolongo Bellón J, Wilmes S, Warda W, Pohler E, Fyfe PK, Cozzani A, Ferrand C, Walter MR, Mitra S, Piehler J, Moraga I. Gorby C, et al. Sci Signal. 2020 Sep 15;13(649):eabc0653. doi: 10.1126/scisignal.abc0653. Sci Signal. 2020. PMID: 32934073 Free PMC article.
We generated an IL-10 mutant with enhanced affinity for its IL-10Rbeta receptor using yeast surface display. ...Our study provides insights into how IL-10 receptor complex stability fine-tunes IL-10 biology and opens new opportunities to revitalize fai …
We generated an IL-10 mutant with enhanced affinity for its IL-10Rbeta receptor using yeast surface display. ...Our study prov …
Atherosclerosis: perspectives of anti-inflammatory therapy.
Nasonov EL, Popkova TV. Nasonov EL, et al. Ter Arkh. 2018 May 11;90(5):4-12. doi: 10.26442/terarkh201890514-12. Ter Arkh. 2018. PMID: 30701884 Review.
The mechanisms of atherosclerosis associated with IL-1beta determine the ability of cholesterol crystals and other "Pro-atherogenic" factors to induce the synthesis of IL-1beta by activating NLRP3 inflammasome. The mechanisms of atherosclerosis associated with IL …
The mechanisms of atherosclerosis associated with IL-1beta determine the ability of cholesterol crystals and other "Pro-atherogenic" …
IL-33 Is a Negative Regulator of Vaccine-Induced Antigen-Specific Cellular Immunity.
O'Grady K, Hearnden CCH, Bento D, Oleszycka E, Andersen P, Muñoz-Wolf N, Lavelle EC. O'Grady K, et al. J Immunol. 2019 Feb 15;202(4):1145-1152. doi: 10.4049/jimmunol.1800833. Epub 2019 Jan 14. J Immunol. 2019. PMID: 30642984
The cytokine IL-33 is a well-established inducer of Th2 responses. However, roles for IL-33 in promoting CD8, Th1, and T regulatory cell responses have also emerged. ...In contrast to the effect on cellular immunity, Ab responses were comparable between vaccinated w …
The cytokine IL-33 is a well-established inducer of Th2 responses. However, roles for IL-33 in promoting CD8, Th1, and T regul …
200,357 results
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