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1965 2
1968 1
1970 1
1972 1
1974 3
1975 3
1976 3
1977 2
1978 2
1979 2
1980 2
1981 1
1982 4
1983 7
1984 5
1985 7
1986 7
1987 9
1988 16
1989 13
1990 12
1991 24
1992 23
1993 26
1994 19
1995 25
1996 32
1997 20
1998 23
1999 19
2000 28
2001 45
2002 42
2003 49
2004 69
2005 73
2006 86
2007 79
2008 97
2009 109
2010 133
2011 211
2012 233
2013 280
2014 437
2015 599
2016 826
2017 935
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2019 1140
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2021 1661
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2024 703

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The following term was not found in PubMed: Alviya
Page 1
Insulin/insulin-like growth factor signaling in C. elegans.
Murphy CT, Hu PJ. Murphy CT, et al. WormBook. 2013 Dec 26:1-43. doi: 10.1895/wormbook.1.164.1. WormBook. 2013. PMID: 24395814 Free PMC article. Review.
The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism, growth, development, longevity, and behavior. ...Originally identified based on its role in the regulation of larval development and aging, IIS also controls a host of other …
The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism, growth, development, longevity, and beha …
DAF-16/FoxO in Caenorhabditis elegans and Its Role in Metabolic Remodeling.
Zečić A, Braeckman BP. Zečić A, et al. Cells. 2020 Jan 2;9(1):109. doi: 10.3390/cells9010109. Cells. 2020. PMID: 31906434 Free PMC article. Review.
The major regulator of DAF-16 activity is the insulin/insulin-like growth factor 1 (IGF-1) signaling (IIS) pathway, reduction of which leads to lifespan extension in worms, flies, mice, and humans. In C. elegans daf-2 mutants, reduced IIS leads to a heterochronic ac …
The major regulator of DAF-16 activity is the insulin/insulin-like growth factor 1 (IGF-1) signaling (IIS) pathway, reduction of whic …
Class-IIS restriction enzymes--a review.
Szybalski W, Kim SC, Hasan N, Podhajska AJ. Szybalski W, et al. Gene. 1991 Apr;100:13-26. doi: 10.1016/0378-1119(91)90345-c. Gene. 1991. PMID: 2055464 Review.
The recognition sequences of ENases-IIS are totally (or partially) asymmetric and all of the characterized ENases-IIS are monomeric. A total of 35 ENases-IIS are described (80, if all isoschizomers are taken into consideration) together with ten related ENase …
The recognition sequences of ENases-IIS are totally (or partially) asymmetric and all of the characterized ENases-IIS are mono …
Intersection of policy and Immunization Information Systems (IIS).
Heersema LA, Cunniff L, Eiden AL, Sharma I, Mishra J, Bhatti A. Heersema LA, et al. BMC Public Health. 2023 Sep 20;23(1):1828. doi: 10.1186/s12889-023-16457-2. BMC Public Health. 2023. PMID: 37730618 Free PMC article. Review.
We sought to highlight the evolution of IIS policy over the last two decades, as IIS play a pivotal role in achieving equitable and high vaccine uptake. ...CONCLUSIONS: In the United States (US), IIS are implemented and managed at the state and local level, c …
We sought to highlight the evolution of IIS policy over the last two decades, as IIS play a pivotal role in achieving equitabl …
Irinotecan-Induced Steatohepatitis: Current Insights.
Han J, Zhang J, Zhang C. Han J, et al. Front Oncol. 2021 Oct 11;11:754891. doi: 10.3389/fonc.2021.754891. eCollection 2021. Front Oncol. 2021. PMID: 34707997 Free PMC article. Review.
The major risks and predisposing factors for IIS include high body mass index (BMI) or obesity, diabetes, and high-fat diet. ...This review summarizes the current knowledge and research progress on IIS....
The major risks and predisposing factors for IIS include high body mass index (BMI) or obesity, diabetes, and high-fat diet. ...This …
Insulin and Memory in Invertebrates.
Nakai J, Chikamoto N, Fujimoto K, Totani Y, Hatakeyama D, Dyakonova VE, Ito E. Nakai J, et al. Front Behav Neurosci. 2022 Apr 26;16:882932. doi: 10.3389/fnbeh.2022.882932. eCollection 2022. Front Behav Neurosci. 2022. PMID: 35558436 Free PMC article. Review.
In the present review, therefore, we refer to these peptides as ILP/IGF signaling (IIS) in invertebrates, and discuss the role of IIS in memory formation after classical conditioning in invertebrates. In the arthropod Drosophila melanogaster, IIS is involved …
In the present review, therefore, we refer to these peptides as ILP/IGF signaling (IIS) in invertebrates, and discuss the role of …
Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species.
Mathew R, Pal Bhadra M, Bhadra U. Mathew R, et al. Biogerontology. 2017 Feb;18(1):35-53. doi: 10.1007/s10522-016-9670-8. Epub 2017 Jan 18. Biogerontology. 2017. PMID: 28101820 Review.
Nutrient sensing pathways that maintain glucose homeostasis in body are involved in regulation of aging. Insulin/insulin-like growth factor-1 (IGF-1) signalling (IIS) pathway was the first nutrient sensing pathway discovered to affect the aging process. ...Epigenetic machi …
Nutrient sensing pathways that maintain glucose homeostasis in body are involved in regulation of aging. Insulin/insulin-like growth factor- …
The Role of MicroRNAs in Hepatoblastoma Tumors.
Cristóbal I, Sanz-Álvarez M, Luque M, Caramés C, Rojo F, García-Foncillas J. Cristóbal I, et al. Cancers (Basel). 2019 Mar 22;11(3):409. doi: 10.3390/cancers11030409. Cancers (Basel). 2019. PMID: 30909459 Free PMC article. Review.
Genetic Reduction of Insulin Signaling Mitigates Amyloid-β Deposition by Promoting Expression of Extracellular Matrix Proteins in the Brain.
Sano T, Ochiai T, Nagayama T, Nakamura A, Kubota N, Kadowaki T, Wakabayashi T, Iwatsubo T. Sano T, et al. J Neurosci. 2023 Oct 25;43(43):7226-7241. doi: 10.1523/JNEUROSCI.0071-23.2023. Epub 2023 Sep 12. J Neurosci. 2023. PMID: 37699718 Free PMC article.
The insulin/IGF-1 signaling (IIS) regulates a wide range of biological processes, including aging and lifespan, and has also been implicated in the pathogenesis of Alzheimer's disease (AD). ...In AD mouse models, genetic deletion of key IIS molecules markedly reduce …
The insulin/IGF-1 signaling (IIS) regulates a wide range of biological processes, including aging and lifespan, and has also been imp …
Wnt/TLR Dialog in Neuroinflammation, Relevance in Alzheimer's Disease.
Zolezzi JM, Inestrosa NC. Zolezzi JM, et al. Front Immunol. 2017 Feb 24;8:187. doi: 10.3389/fimmu.2017.00187. eCollection 2017. Front Immunol. 2017. PMID: 28286503 Free PMC article. Review.
Different types of pathogens and diverse molecules can activate the IIS via a ligand-receptor mechanism. Cytokine release, recruitment of immunocompetent cells, and inflammation constitute the initial steps in an IIS-mediated response. While balanced IIS acti …
Different types of pathogens and diverse molecules can activate the IIS via a ligand-receptor mechanism. Cytokine release, recruitmen …
12,177 results
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