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GABRB2, a key player in neuropsychiatric disorders and beyond.
Barki M, Xue H. Barki M, et al. Among authors: xue h. Gene. 2022 Jan 30;809:146021. doi: 10.1016/j.gene.2021.146021. Epub 2021 Oct 19. Gene. 2022. PMID: 34673206 Review.
Furthermore, GABRB2 is imprinted and subjected to epigenetic regulation and positive selection. It has been associated with schizophrenia first in Han Chinese, and subsequently validated in other populations. Gabrb2 knockout mice also exhibited schizophrenia-like behavior …
Furthermore, GABRB2 is imprinted and subjected to epigenetic regulation and positive selection. It has been associated with schizophrenia fi …
GABRB2 Haplotype Association with Heroin Dependence in Chinese Population.
Kim YS, Yang M, Mat WK, Tsang SY, Su Z, Jiang X, Ng SK, Liu S, Hu T, Pun F, Liao Y, Tang J, Chen X, Hao W, Xue H. Kim YS, et al. Among authors: xue h. PLoS One. 2015 Nov 12;10(11):e0142049. doi: 10.1371/journal.pone.0142049. eCollection 2015. PLoS One. 2015. PMID: 26561861 Free PMC article.
GABRB2, a schizophrenia candidate gene coding for GABAA receptor beta2 subunit, is examined for possible association with heroin dependence in Han Chinese population. Four single nucleotide polymorphisms (SNPs) in GABRB2, namely rs6556547 (S1), rs1816071 (S3), rs18016072 ( …
GABRB2, a schizophrenia candidate gene coding for GABAA receptor beta2 subunit, is examined for possible association with heroin dependence …
Social cognitive role of schizophrenia candidate gene GABRB2.
Tsang SY, Zhong S, Mei L, Chen J, Ng SK, Pun FW, Zhao C, Jing B, Chark R, Guo J, Tan Y, Li L, Wang C, Chew SH, Xue H. Tsang SY, et al. Among authors: xue h. PLoS One. 2013 Apr 24;8(4):e62322. doi: 10.1371/journal.pone.0062322. Print 2013. PLoS One. 2013. PMID: 23638040 Free PMC article.
The minor alleles of SNPs rs6556547, rs1816071 and rs187269 in GABRB2 were correlated with high PANSS score for positive symptoms in a Han Chinese schizophrenic cohort, whereas those of rs1816071 and rs1816072 were associated with high antipsychotics dosage in a US Caucasi …
The minor alleles of SNPs rs6556547, rs1816071 and rs187269 in GABRB2 were correlated with high PANSS score for positive symptoms in a Ha …
Genetic variation on the NFKB1 genes associates with the outcomes of HCV infection among Chinese Han population.
Fan HZ, Huang P, Shao JG, Tian T, Li J, Zang F, Liu M, Xue H, Wu JJ, Yu RB, Zhang Y, Yue M. Fan HZ, et al. Among authors: xue h. Infect Genet Evol. 2018 Nov;65:210-215. doi: 10.1016/j.meegid.2018.07.031. Epub 2018 Jul 26. Infect Genet Evol. 2018. PMID: 30056167
CONCLUSION: NFKB1 rs28362491-D allele was functionally associated with the increased risk of susceptibility to HCV infection in the Chinese Han population....
CONCLUSION: NFKB1 rs28362491-D allele was functionally associated with the increased risk of susceptibility to HCV infection in the Chinese …
Genome-wide detection and characterization of positive selection in human populations.
Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF, Lander ES; International HapMap Consortium; Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, Yang H, Zeng C, Gao Y, Hu H, Hu W, Li C, Lin W, Liu S, Pan H, Tang X, Wang J, Wang W, Yu J, Zhang B, Zhang Q, Zhao H, Zhao H, Zhou J, Gabriel SB, Barry R, Blumenstiel B, Camargo A, Defelice M, Faggart M, Goyette M, Gupta S, Moore J, Nguyen H, Onofrio RC, Parkin M, Roy J, Stahl E, Winchester E, Ziaugra L, Altshuler D, Shen Y, Yao Z, Huang W, Chu X, He Y, Jin L, Liu Y, Shen Y, Sun W, Wang H, Wang Y, Wang Y, Xiong X, Xu L, Waye MM, Tsui SK, Xue H, Wong JT, Galver LM, Fan JB, Gunderson K, Murray SS, Oliphant AR, Chee MS, Montpetit A, Chagnon F, Ferretti V, Leboeuf M, Olivier JF, Phillips MS, Roumy S, Sallée C, Verner A, Hudson TJ, Kwok PY, Cai D, Koboldt DC, Miller RD, Pawlikowska L, Taillon-Miller P, Xiao M, Tsui LC, Mak W, Song YQ, Tam PK, Nakamura Y, Kawaguchi T, Kitamoto T, Morizono T, Nagashima A, Ohnishi Y, Sekine A, Tanaka T, Tsunoda T, Deloukas P, Bird CP, D… See abstract for full author list ➔ Sabeti PC, et al. Among authors: xue h. Nature. 2007 Oct 18;449(7164):913-8. doi: 10.1038/nature06250. Nature. 2007. PMID: 17943131 Free PMC article.
Alu-associated enhancement of single nucleotide polymorphisms in the human genome.
Ng SK, Xue H. Ng SK, et al. Among authors: xue h. Gene. 2006 Mar 1;368:110-6. doi: 10.1016/j.gene.2005.10.034. Epub 2005 Dec 27. Gene. 2006. PMID: 16380220
Variations in Alu-SNPs among the HapMap populations of northern and western European ancestry (CEU), Han Chinese from Beijing (CHB), Japanese from Tokyo (JPT), and Yoruba from Ibadan, Nigeria (YRI) indicate that the Alu-SNPs provide useful sequence markers, in addition to …
Variations in Alu-SNPs among the HapMap populations of northern and western European ancestry (CEU), Han Chinese from Beijing (CHB), …
Apolipoprotein B gene 3'VNTR polymorphism: association with plasma lipids and coronary heart disease in Han Chinese.
Yan SK, Song YH, Zhu WL, Yan XW, Xue H, Du H, Chen BS. Yan SK, et al. Among authors: xue h. Clin Chem Lab Med. 2006;44(10):1199-205. doi: 10.1515/CCLM.2006.221. Clin Chem Lab Med. 2006. PMID: 17032131
CONCLUSIONS: APOB gene 3'VNTR polymorphism exerts an impact on lipid metabolism and may contribute to the susceptibility to the development of CHD in Han Chinese....
CONCLUSIONS: APOB gene 3'VNTR polymorphism exerts an impact on lipid metabolism and may contribute to the susceptibility to the development …
Analysis of GABRB2 association with schizophrenia in German population with DNA sequencing and one-label extension method for SNP genotyping.
Yu Z, Chen J, Shi H, Stoeber G, Tsang SY, Xue H. Yu Z, et al. Among authors: xue h. Clin Biochem. 2006 Mar;39(3):210-8. doi: 10.1016/j.clinbiochem.2006.01.009. Epub 2006 Feb 9. Clin Biochem. 2006. PMID: 16472798
This is consistent with our previous finding of association of SNPs in GABRB2 with SCZ susceptibility in Han Chinese. There was a total agreement between the genotyping results from one-label extensions and the results of direct DNA sequencing, thus validating the accuracy …
This is consistent with our previous finding of association of SNPs in GABRB2 with SCZ susceptibility in Han Chinese. There was a tot …
A second generation human haplotype map of over 3.1 million SNPs.
International HapMap Consortium; Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, Yang H, Zeng C, Gao Y, Hu H, Hu W, Li C, Lin W, Liu S, Pan H, Tang X, Wang J, Wang W, Yu J, Zhang B, Zhang Q, Zhao H, Zhao H, Zhou J, Gabriel SB, Barry R, Blumenstiel B, Camargo A, Defelice M, Faggart M, Goyette M, Gupta S, Moore J, Nguyen H, Onofrio RC, Parkin M, Roy J, Stahl E, Winchester E, Ziaugra L, Altshuler D, Shen Y, Yao Z, Huang W, Chu X, He Y, Jin L, Liu Y, Shen Y, Sun W, Wang H, Wang Y, Wang Y, Xiong X, Xu L, Waye MM, Tsui SK, Xue H, Wong JT, Galver LM, Fan JB, Gunderson K, Murray SS, Oliphant AR, Chee MS, Montpetit A, Chagnon F, Ferretti V, Leboeuf M, Olivier JF, Phillips MS, Roumy S, Sallée C, Verner A, Hudson TJ, Kwok PY, Cai D, Koboldt DC, Miller RD, Pawlikowska L, Taillon-Miller P, Xiao M, Tsui LC, Mak W, Song YQ, Tam PK, Nakamura Y, Kawaguchi T, Kitamoto T, Morizono T, Nagashima A, Ohnishi Y, Sekine A, Tanaka T, Tsunoda T, Deloukas P, Bird CP, Delgado M, Dermitzakis ET, Gwilliam R, Hunt S, Morrison J, Powell D, Stranger BE, Whittaker P, Bentley DR, Daly MJ, de Bakker PI, Barre… See abstract for full author list ➔ International HapMap Consortium, et al. Among authors: xue h. Nature. 2007 Oct 18;449(7164):851-61. doi: 10.1038/nature06258. Nature. 2007. PMID: 17943122 Free PMC article.
14 results