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HO-1089 and HO-1197, Novel Herbal Formulas, Have Antitumor Effects via Suppression of PLK1 (Polo-like Kinase 1) Expression in Hepatocellular Carcinoma.
Song Y, Lee SY, Kim S, Choi I, Kim N, Park J, Seo HR. Song Y, et al. Cancers (Basel). 2023 Jan 30;15(3):851. doi: 10.3390/cancers15030851. Cancers (Basel). 2023. PMID: 36765811 Free PMC article.
Biological pathways involved in metabolism and the mitotic cell cycle were suppressed in HO-1089-treated HCC cells. HO-1089 attenuated expression of the G2/M phase regulatory protein, PLK1 (polo-like kinase 1), in HCC cells. ...The use of HO-1197, a novel her …
Biological pathways involved in metabolism and the mitotic cell cycle were suppressed in HO-1089-treated HCC cells. HO-1089 at …
Anti-allergic rhinitis activity of alpha-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling.
Van Nguyen T, Piao CH, Fan YJ, Shin DU, Kim SY, Song HJ, Song CH, Shin HS, Chai OH. Van Nguyen T, et al. Sci Rep. 2020 Jul 27;10(1):12528. doi: 10.1038/s41598-020-69234-1. Sci Rep. 2020. PMID: 32719431 Free PMC article.
LA greatly enhanced the nuclear factor erythroid-derived 2/heme oxygenase 1 (Nrf2/HO-1) pathway signaling and inhibited the activation of NF-kappaB/IkappaB, markedly suppressed the levels of pro-inflammatory cytokines TNF-alpha, IL-1beta, IL-6, IL-8 and chemokine COX-2. .. …
LA greatly enhanced the nuclear factor erythroid-derived 2/heme oxygenase 1 (Nrf2/HO-1) pathway signaling and inhibited the activatio …