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Advanced maritime adaptation in the western Pacific coastal region extends back to 35,000-30,000 years before present.
Fujita M, Yamasaki S, Katagiri C, Oshiro I, Sano K, Kurozumi T, Sugawara H, Kunikita D, Matsuzaki H, Kano A, Okumura T, Sone T, Fujita H, Kobayashi S, Naruse T, Kondo M, Matsu'ura S, Suwa G, Kaifu Y. Fujita M, et al. Among authors: sugawara h. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11184-11189. doi: 10.1073/pnas.1607857113. Epub 2016 Sep 16. Proc Natl Acad Sci U S A. 2016. PMID: 27638208 Free PMC article.
Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling.
Yamagishi S, Abe R, Inagaki Y, Nakamura K, Sugawara H, Inokuma D, Nakamura H, Shimizu T, Takeuchi M, Yoshimura A, Bucala R, Shimizu H, Imaizumi T. Yamagishi S, et al. Among authors: sugawara h. Am J Pathol. 2004 Dec;165(6):1865-74. doi: 10.1016/s0002-9440(10)63239-7. Am J Pathol. 2004. PMID: 15579431 Free PMC article.