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The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling.
Choi YH, Lee SN, Aoyagi H, Yamasaki Y, Yoo JY, Park B, Shin DM, Yoon HG, Yoon JH. Choi YH, et al. Among authors: aoyagi h. J Biol Chem. 2011 Sep 30;286(39):34199-214. doi: 10.1074/jbc.M111.247684. Epub 2011 Aug 10. J Biol Chem. 2011. PMID: 21832046 Free PMC article.