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2016 1
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2020 3
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Page 1
A single-cell map of antisense oligonucleotide activity in the brain.
Mortberg MA, Gentile JE, Nadaf NM, Vanderburg C, Simmons S, Dubinsky D, Slamin A, Maldonado S, Petersen CL, Jones N, Kordasiewicz HB, Zhao HT, Vallabh SM, Minikel EV. Mortberg MA, et al. Among authors: zhao ht. Nucleic Acids Res. 2023 Aug 11;51(14):7109-7124. doi: 10.1093/nar/gkad371. Nucleic Acids Res. 2023. PMID: 37188501 Free PMC article.
Antisense oligonucleotides extend survival of prion-infected mice.
Raymond GJ, Zhao HT, Race B, Raymond LD, Williams K, Swayze EE, Graffam S, Le J, Caron T, Stathopoulos J, O'Keefe R, Lubke LL, Reidenbach AG, Kraus A, Schreiber SL, Mazur C, Cabin DE, Carroll JB, Minikel EV, Kordasiewicz H, Caughey B, Vallabh SM. Raymond GJ, et al. JCI Insight. 2019 Jul 30;5(16):e131175. doi: 10.1172/jci.insight.131175. JCI Insight. 2019. PMID: 31361599 Free PMC article.
Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.
Elitt MS, Barbar L, Shick HE, Powers BE, Maeno-Hikichi Y, Madhavan M, Allan KC, Nawash BS, Gevorgyan AS, Hung S, Nevin ZS, Olsen HE, Hitomi M, Schlatzer DM, Zhao HT, Swayze A, LePage DF, Jiang W, Conlon RA, Rigo F, Tesar PJ. Elitt MS, et al. Among authors: zhao ht. Nature. 2020 Sep;585(7825):397-403. doi: 10.1038/s41586-020-2494-3. Epub 2020 Jul 1. Nature. 2020. PMID: 32610343 Free PMC article.
A single-cell map of antisense oligonucleotide activity in the brain.
Mortberg MA, Gentile JE, Nadaf N, Vanderburg C, Simmons S, Dubinsky D, Slamin A, Maldonado S, Petersen CL, Jones N, Kordasiewicz HB, Zhao HT, Vallabh SM, Minikel EV. Mortberg MA, et al. Among authors: zhao ht. bioRxiv [Preprint]. 2023 Feb 14:2023.02.14.528473. doi: 10.1101/2023.02.14.528473. bioRxiv. 2023. PMID: 36824749 Free PMC article. Updated. Preprint.
Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS.
Mortberg MA, Zhao HT, Reidenbach AG, Gentile JE, Kuhn E, O'Moore J, Dooley PM, Connors TR, Mazur C, Allen SW, Trombetta BA, McManus A, Moore MR, Liu J, Cabin DE, Kordasiewicz HB, Mathews J, Arnold SE, Vallabh SM, Minikel EV. Mortberg MA, et al. Among authors: zhao ht. JCI Insight. 2022 Mar 22;7(6):e156532. doi: 10.1172/jci.insight.156532. JCI Insight. 2022. PMID: 35133987 Free PMC article.
16 results