Fabrication of functionalized carbon nanotube buckypaper electrodes for application in glucose biosensors

Henry Papa; Melissa Gaillard; Leon Gonzalez; Jhunu Chatterjee

doi:10.3390/bios4040449

Fabrication of functionalized carbon nanotube buckypaper electrodes for application in glucose biosensors

Biosensors (Basel). 2014 Nov 11;4(4):449-60. doi: 10.3390/bios4040449. eCollection 2014 Dec.

Authors

Henry Papa¹, Melissa Gaillard², Leon Gonzalez³, Jhunu Chatterjee⁴

Affiliations

¹ High Performance Materials Institute, Florida State University, 2005 Levy Avenue, Tallahassee, FL 32310, USA; E-Mails: hap09@my.fsu.edu (H.P.); mgailla@g.clemson.edu (M.G.) ; Department of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, 2525 Pottsdamer Street, Tallahassee, FL 32310, USA; E-Mail: lhg12@my.fsu.edu.
² High Performance Materials Institute, Florida State University, 2005 Levy Avenue, Tallahassee, FL 32310, USA; E-Mails: hap09@my.fsu.edu (H.P.); mgailla@g.clemson.edu (M.G.) ; Department of Biomedical Engineering, Clemson University, Clemson, SC 29634, USA.
³ Department of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, 2525 Pottsdamer Street, Tallahassee, FL 32310, USA; E-Mail: lhg12@my.fsu.edu.
⁴ High Performance Materials Institute, Florida State University, 2005 Levy Avenue, Tallahassee, FL 32310, USA; E-Mails: hap09@my.fsu.edu (H.P.); mgailla@g.clemson.edu (M.G.).

Abstract

A highly sensitive glucose detection method was developed using functionalized carbon nanotube buckypaper as a free standing electrode in an electrochemical biosensor. Glucose oxidase was immobilized onto various buckypaper samples in order to oxidize glucose resulting in a measureable current/voltage signal output of the biosensor. Cyclic voltammetry (CV) and amperometry were utilized to determine the sensitivity of these buckypaper electrodes. Sensors of three different types of buckypaper were prepared and compared. These modified buckypaper electrode-based sensors showed much higher sensitivity to glucose compared to other electrochemical glucose sensors.

Keywords: buckypaper; carbon nanotube; electrochemical biosensor; glucose sensor; gold nanoparticles.