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Page 1
Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.
Metabolites. 2021 Feb 13;11(2):109. doi: 10.3390/metabo11020109.
Metabolites. 2021.
PMID: 33668509
Free PMC article.
Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.
Taglang C, Batsios G, Mukherjee J, Tran M, Gillespie AM, Hong D, Ronen SM, Artee Luchman H, Pieper RO, Viswanath P.
Taglang C, et al. Among authors: artee luchman h.
Neuro Oncol. 2022 Jul 1;24(7):1101-1112. doi: 10.1093/neuonc/noac022.
Neuro Oncol. 2022.
PMID: 35091751
Free PMC article.
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Rational Drug Design of Targeted and Enzyme-Cleavable Vitamin E Analogs as a Neoadjuvant to Chemotherapy: In Vitro and In Vivo Evaluation on Reduction of the Cardiotoxicity Side Effect of Doxorubicin.
Pandurangi RS, Cseh O, Luchman HA, Ma CX, Senadheera SN, Forrest ML.
Pandurangi RS, et al. Among authors: luchman ha.
ACS Pharmacol Transl Sci. 2023 Feb 6;6(3):372-386. doi: 10.1021/acsptsci.2c00091. eCollection 2023 Mar 10.
ACS Pharmacol Transl Sci. 2023.
PMID: 36926453
Free PMC article.
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Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.
Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM.
Viswanath P, et al. Among authors: luchman ha.
Cancer Metab. 2018 Apr 3;6:3. doi: 10.1186/s40170-018-0178-3. eCollection 2018.
Cancer Metab. 2018.
PMID: 29619216
Free PMC article.
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2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas.
Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM.
Viswanath P, et al. Among authors: luchman ha.
Cancer Res. 2018 May 1;78(9):2290-2304. doi: 10.1158/0008-5472.CAN-17-2926. Epub 2018 Jan 22.
Cancer Res. 2018.
PMID: 29358170
Free PMC article.
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The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model.
Jensen KV, Cseh O, Aman A, Weiss S, Luchman HA.
Jensen KV, et al. Among authors: luchman ha.
PLoS One. 2017 Dec 18;12(12):e0189670. doi: 10.1371/journal.pone.0189670. eCollection 2017.
PLoS One. 2017.
PMID: 29253028
Free PMC article.
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