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The direct renin inhibitor aliskiren localizes and persists in rat kidneys.
Am J Physiol Renal Physiol. 2013 Dec 1;305(11):F1593-602. doi: 10.1152/ajprenal.00655.2012. Epub 2013 Aug 7.
Am J Physiol Renal Physiol. 2013.
PMID: 23926182
Free article.
Pharmacokinetic and technical comparison of Sandostatin® LAR® and other formulations of long-acting octreotide.
Petersen H, Bizec JC, Schuetz H, Delporte ML.
Petersen H, et al. Among authors: schuetz h.
BMC Res Notes. 2011 Sep 9;4:344. doi: 10.1186/1756-0500-4-344.
BMC Res Notes. 2011.
PMID: 21906300
Free PMC article.
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Biocompatibility of an injectable in situ forming depot for peptide delivery.
Schoenhammer K, Boisclair J, Schuetz H, Petersen H, Goepferich A.
Schoenhammer K, et al. Among authors: schuetz h.
J Pharm Sci. 2010 Oct;99(10):4390-9. doi: 10.1002/jps.22149.
J Pharm Sci. 2010.
PMID: 20665506
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Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren.
Vaidyanathan S, Camenisch G, Schuetz H, Reynolds C, Yeh CM, Bizot MN, Dieterich HA, Howard D, Dole WP.
Vaidyanathan S, et al. Among authors: schuetz h.
J Clin Pharmacol. 2008 Nov;48(11):1323-38. doi: 10.1177/0091270008323258. Epub 2008 Sep 10.
J Clin Pharmacol. 2008.
PMID: 18784280
Clinical Trial.
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Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats.
Feldman DL, Jin L, Xuan H, Contrepas A, Zhou Y, Webb RL, Mueller DN, Feldt S, Cumin F, Maniara W, Persohn E, Schuetz H, Jan Danser AH, Nguyen G.
Feldman DL, et al. Among authors: schuetz h.
Hypertension. 2008 Jul;52(1):130-6. doi: 10.1161/HYPERTENSIONAHA.107.108845. Epub 2008 May 19.
Hypertension. 2008.
PMID: 18490518
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