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Novel (S)-(-)- and R-(+)-seco-iso-cyclopropylfurano[e]indoline-5,6,7-trimethoxyindole-2-carboxamide (iso-CFI) analogs of duocarmycin C2: synthesis and biological evaluation.
Med Chem. 2006 Mar;2(2):139-46. doi: 10.2174/157340606776056188.
Med Chem. 2006.
PMID: 16787363
Unexpected syntheses of seco-cyclopropyltetrahydroquinolines - from a radical 5-exo-trig cyclization reaction: analogs of CC-1065 and the duocarmycins.
Pati H, Howard T, Townes H, Lingerfelt B, McNulty L, Lee M.
Pati H, et al. Among authors: townes h.
Molecules. 2004 Feb 28;9(3):125-33. doi: 10.3390/90300125.
Molecules. 2004.
PMID: 18007417
Free PMC article.
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A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
Kupchinsky S, Centioni S, Howard T, Trzupek J, Roller S, Carnahan V, Townes H, Purnell B, Price C, Handl H, Summerville K, Johnson K, Toth J, Hudson S, Kiakos K, Hartley JA, Lee M.
Kupchinsky S, et al. Among authors: townes h.
Bioorg Med Chem. 2004 Dec 1;12(23):6221-36. doi: 10.1016/j.bmc.2004.08.051.
Bioorg Med Chem. 2004.
PMID: 15519165
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Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.
Howard TT, Lingerfelt BM, Purnell BL, Scott AE, Price CA, Townes HM, McNulty L, Handl HL, Summerville K, Hudson SJ, Bowen JP, Kiakos K, Hartley JA, Lee M.
Howard TT, et al. Among authors: townes hm.
Bioorg Med Chem. 2002 Sep;10(9):2941-52. doi: 10.1016/s0968-0896(02)00157-8.
Bioorg Med Chem. 2002.
PMID: 12110316
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