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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 5
2003 2
2004 5
2005 8
2006 6
2007 4
2008 6
2009 6
2010 7
2011 12
2012 3
2013 11
2014 8
2015 5
2016 10
2017 14
2018 2
2019 9
2020 15
2021 8
2022 7
2023 13
2024 2

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153 results

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Page 1
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: hubner h. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843 Free PMC article.
Structure-based discovery of opioid analgesics with reduced side effects.
Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, Scherrer G, Kobilka BK, Gmeiner P, Roth BL, Shoichet BK. Manglik A, et al. Among authors: hubner h. Nature. 2016 Sep 8;537(7619):185-190. doi: 10.1038/nature19112. Epub 2016 Aug 17. Nature. 2016. PMID: 27533032 Free PMC article.
Fluorescent ligands for dopamine D2/D3 receptors.
Allikalt A, Purkayastha N, Flad K, Schmidt MF, Tabor A, Gmeiner P, Hübner H, Weikert D. Allikalt A, et al. Among authors: hubner h. Sci Rep. 2020 Dec 14;10(1):21842. doi: 10.1038/s41598-020-78827-9. Sci Rep. 2020. PMID: 33318558 Free PMC article.
Discovery of Novel Nonpeptidic PAR2 Ligands.
Klösel I, Schmidt MF, Kaindl J, Hübner H, Weikert D, Gmeiner P. Klösel I, et al. Among authors: hubner h. ACS Med Chem Lett. 2020 May 22;11(6):1316-1323. doi: 10.1021/acsmedchemlett.0c00154. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551018 Free PMC article.
Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists.
Wang H, Hetzer F, Huang W, Qu Q, Meyerowitz J, Kaindl J, Hübner H, Skiniotis G, Kobilka BK, Gmeiner P. Wang H, et al. Among authors: hubner h. Angew Chem Int Ed Engl. 2022 Jun 27;61(26):e202200269. doi: 10.1002/anie.202200269. Epub 2022 Apr 29. Angew Chem Int Ed Engl. 2022. PMID: 35385593 Free PMC article.
153 results