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Did you mean han jun bo (17 results)?
MutSα and MutSβ as size-dependent cellular determinants for prime editing in human embryonic stem cells.
Park JC, Kim YJ, Han JH, Kim D, Park MJ, Kim J, Jang HK, Bae S, Cha HJ. Park JC, et al. Among authors: han jh. Mol Ther Nucleic Acids. 2023 May 18;32:914-922. doi: 10.1016/j.omtn.2023.05.015. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37346976 Free PMC article.
Considering the high demand for prime editors (PEs), it is imperative to characterize the key molecular determinants of PE outcomes in hPSCs. Through homozygous knockout (KO) of MMR pathway key proteins MSH2, MSH3, and MSH6, we reveal that MutSalpha and MutSbeta determine …
Considering the high demand for prime editors (PEs), it is imperative to characterize the key molecular determinants of PE outcomes in hPSCs …
Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice.
Wang R, Sheps JA, Liu L, Han J, Chen PSK, Lamontagne J, Wilson PD, Welch I, Borchers CH, Ling V. Wang R, et al. Among authors: han j. J Lipid Res. 2019 Jan;60(1):85-97. doi: 10.1194/jlr.M088070. Epub 2018 Nov 11. J Lipid Res. 2019. PMID: 30416103 Free PMC article.
We asked whether the highly hydrophilic bile acids generated by Bsep(-/-) mice could protect Mdr2(-/-) mice from progressive liver damage. We generated double-KO (DKO: Bsep(-/-) and Mdr2(-/-) ) mice. Their bile acid composition resembles that of Bsep(-/-) mice, with increa …
We asked whether the highly hydrophilic bile acids generated by Bsep(-/-) mice could protect Mdr2(-/-) mice from progressive liver damage. W …
Suppression of NLRP3 Inflammasome by Erythropoietin via the EPOR/JAK2/STAT3 Pathway Contributes to Attenuation of Acute Lung Injury in Mice.
Cao F, Tian X, Li Z, Lv Y, Han J, Zhuang R, Cheng B, Gong Y, Ying B, Jin S, Gao Y. Cao F, et al. Among authors: han j. Front Pharmacol. 2020 Mar 19;11:306. doi: 10.3389/fphar.2020.00306. eCollection 2020. Front Pharmacol. 2020. PMID: 32265704 Free PMC article.
However, all the beneficial effects of EPO on ALI and modulation NLRP3 inflammasome were remarkably abrogated by the inhibition of EPOR/JAK2/STAT3 pathway and knockout (KO) of NLRP3 gene. Taken together, this study indicates that EPO can effectively attenuate LPS-induced l …
However, all the beneficial effects of EPO on ALI and modulation NLRP3 inflammasome were remarkably abrogated by the inhibition of EPOR/JAK2 …