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Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine.
Xiang AX, Webber SE, Kerr BM, Rueden EJ, Lennox JR, Haley GJ, Wang T, Ng JS, Herbert MR, Clark DL, Banh VN, Li W, Fletcher SP, Steffy KR, Bartkowski DM, Kirkovsky LI, Bauman LA, Averett DR. Xiang AX, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):635-40. doi: 10.1080/15257770701490472. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066870 Clinical Trial.