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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 7
2004 3
2005 4
2006 11
2007 4
2008 7
2009 14
2010 14
2011 12
2012 15
2013 30
2014 38
2015 19
2016 37
2017 51
2018 42
2019 38
2020 53
2021 66
2022 81
2023 88
2024 24

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596 results

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Page 1
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: yang h. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z. Gao Y, et al. Among authors: yang h. Science. 2020 May 15;368(6492):779-782. doi: 10.1126/science.abb7498. Epub 2020 Apr 10. Science. 2020. PMID: 32277040 Free PMC article.
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir.
Iketani S, Mohri H, Culbertson B, Hong SJ, Duan Y, Luck MI, Annavajhala MK, Guo Y, Sheng Z, Uhlemann AC, Goff SP, Sabo Y, Yang H, Chavez A, Ho DD. Iketani S, et al. Among authors: yang h. Nature. 2023 Jan;613(7944):558-564. doi: 10.1038/s41586-022-05514-2. Epub 2022 Nov 9. Nature. 2023. PMID: 36351451 Free PMC article.
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir.
Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, Bian Q, Wang H, Sun H, Hong SJ, Culbertson B, Mohri H, Luck MI, Zhu Y, Liu X, Lu Y, Yang X, Yang K, Sabo Y, Chavez A, Goff SP, Rao Z, Ho DD, Yang H. Duan Y, et al. Among authors: yang h. Nature. 2023 Oct;622(7982):376-382. doi: 10.1038/s41586-023-06609-0. Epub 2023 Sep 11. Nature. 2023. PMID: 37696289
A parabrachial-hypothalamic parallel circuit governs cold defense in mice.
Yang WZ, Xie H, Du X, Zhou Q, Xiao Y, Zhao Z, Jia X, Xu J, Zhang W, Cai S, Li Z, Fu X, Hua R, Cai J, Chang S, Sun J, Sun H, Xu Q, Ni X, Tu H, Zheng R, Xu X, Wang H, Fu Y, Wang L, Li X, Yang H, Yao Q, Yu T, Shen Q, Shen WL. Yang WZ, et al. Among authors: yang h. Nat Commun. 2023 Aug 15;14(1):4924. doi: 10.1038/s41467-023-40504-6. Nat Commun. 2023. PMID: 37582782 Free PMC article.
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: yang h. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Hypothalamic warm-sensitive neurons require TRPC4 channel for detecting internal warmth and regulating body temperature in mice.
Zhou Q, Fu X, Xu J, Dong S, Liu C, Cheng D, Gao C, Huang M, Liu Z, Ni X, Hua R, Tu H, Sun H, Shen Q, Chen B, Zhang J, Zhang L, Yang H, Hu J, Yang W, Pei W, Yao Q, Sheng X, Zhang J, Yang WZ, Shen WL. Zhou Q, et al. Among authors: yang h. Neuron. 2023 Feb 1;111(3):387-404.e8. doi: 10.1016/j.neuron.2022.11.008. Epub 2022 Dec 6. Neuron. 2023. PMID: 36476978 Free article.
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors.
Zang Y, Su M, Wang Q, Cheng X, Zhang W, Zhao Y, Chen T, Jiang Y, Shen Q, Du J, Tan Q, Wang P, Gao L, Jin Z, Zhang M, Li C, Zhu Y, Feng B, Tang B, Xie H, Wang MW, Zheng M, Pan X, Yang H, Xu Y, Wu B, Zhang L, Rao Z, Yang X, Jiang H, Xiao G, Zhao Q, Li J. Zang Y, et al. Among authors: yang h. Protein Cell. 2022 Sep 28;14(1):17-27. doi: 10.1093/procel/pwac016. eCollection 2023 Jan. Protein Cell. 2022. PMID: 36726755 Free PMC article.
596 results