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Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial.
Ramacciotti E, Barile Agati L, Calderaro D, Aguiar VCR, Spyropoulos AC, de Oliveira CCC, Lins Dos Santos J, Volpiani GG, Sobreira ML, Joviliano EE, Bohatch Júnior MS, da Fonseca BAL, Ribeiro MS, Dusilek C, Itinose K, Sanches SMV, de Almeida Araujo Ramos K, de Moraes NF, Tierno PFGMM, de Oliveira ALML, Tachibana A, Chate RC, Santos MVB, de Menezes Cavalcante BB, Moreira RCR, Chang C, Tafur A, Fareed J, Lopes RD; MICHELLE investigators. Ramacciotti E, et al. Lancet. 2022 Jan 1;399(10319):50-59. doi: 10.1016/S0140-6736(21)02392-8. Epub 2021 Dec 15. Lancet. 2022. PMID: 34921756 Free PMC article. Clinical Trial.
BACKGROUND: Patients hospitalised with COVID-19 are at risk for thrombotic events after discharge; the role of extended thromboprophylaxis in this population is unknown. ...The primary efficacy outcome occurred in five (3%) of 159 patients assigned to rivaroxaban an …
BACKGROUND: Patients hospitalised with COVID-19 are at risk for thrombotic events after discharge; the role of extended thromb …
Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial.
Tomazini BM, Maia IS, Cavalcanti AB, Berwanger O, Rosa RG, Veiga VC, Avezum A, Lopes RD, Bueno FR, Silva MVAO, Baldassare FP, Costa ELV, Moura RAB, Honorato MO, Costa AN, Damiani LP, Lisboa T, Kawano-Dourado L, Zampieri FG, Olivato GB, Righy C, Amendola CP, Roepke RML, Freitas DHM, Forte DN, Freitas FGR, Fernandes CCF, Melro LMG, Junior GFS, Morais DC, Zung S, Machado FR, Azevedo LCP; COALITION COVID-19 Brazil III Investigators. Tomazini BM, et al. JAMA. 2020 Oct 6;324(13):1307-1316. doi: 10.1001/jama.2020.17021. JAMA. 2020. PMID: 32876695 Free PMC article. Clinical Trial.
IMPORTANCE: Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) is associated with substantial mortality and use of health care resources. ...Patients with COVID-19 and moderate to severe ARDS, according to the Berlin …
IMPORTANCE: Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) is associated with substanti …
Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial.
Murai IH, Fernandes AL, Sales LP, Pinto AJ, Goessler KF, Duran CSC, Silva CBR, Franco AS, Macedo MB, Dalmolin HHH, Baggio J, Balbi GGM, Reis BZ, Antonangelo L, Caparbo VF, Gualano B, Pereira RMR. Murai IH, et al. JAMA. 2021 Mar 16;325(11):1053-1060. doi: 10.1001/jama.2020.26848. JAMA. 2021. PMID: 33595634 Free PMC article. Clinical Trial.
IMPORTANCE: The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear. OBJECTIVE: To investigate the effect of a single high dose of vitamin D3 on hospital length of stay in patients with COVID-19. DESIGN, SETTIN …
IMPORTANCE: The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear. OBJECTIVE: To i …
Long-term respiratory follow-up of ICU hospitalized COVID-19 patients: Prospective cohort study.
Ribeiro Carvalho CR, Lamas CA, Chate RC, Salge JM, Sawamura MVY, de Albuquerque ALP, Toufen Junior C, Lima DM, Garcia ML, Scudeller PG, Nomura CH, Gutierrez MA, Baldi BG; HCFMUSP Covid-19 Study Group. Ribeiro Carvalho CR, et al. PLoS One. 2023 Jan 20;18(1):e0280567. doi: 10.1371/journal.pone.0280567. eCollection 2023. PLoS One. 2023. PMID: 36662879 Free PMC article.
BACKGROUND: Coronavirus disease (COVID-19) survivors exhibit multisystemic alterations after hospitalization. ...METHODS: A prospective cohort study of COVID-19 patients admitted to a tertiary hospital ICU in Brazil (March-August/2020), and foll …
BACKGROUND: Coronavirus disease (COVID-19) survivors exhibit multisystemic alterations after hospitalization. ...METHODS: A pr …
Post-COVID-19 psychiatric and cognitive morbidity: Preliminary findings from a Brazilian cohort study.
Damiano RF, Caruso MJG, Cincoto AV, de Almeida Rocca CC, de Pádua Serafim A, Bacchi P, Guedes BF, Brunoni AR, Pan PM, Nitrini R, Beach S, Fricchione G, Busatto G, Miguel EC, Forlenza OV; HCFMUSP COVID-19 Study Group. Damiano RF, et al. Gen Hosp Psychiatry. 2022 Mar-Apr;75:38-45. doi: 10.1016/j.genhosppsych.2022.01.002. Epub 2022 Jan 6. Gen Hosp Psychiatry. 2022. PMID: 35134702 Free PMC article.
OBJECTIVE: The present study aims to investigate the occurrence of psychiatric and cognitive impairments in a cohort of survivors of moderate or severe forms of COVID-19. ...Psychiatric or cognitive outcomes were not associated with any clinical variables rel …
OBJECTIVE: The present study aims to investigate the occurrence of psychiatric and cognitive impairments in a cohort of survivors of …
COVID-19 Vaccines Confer Protection in Hospitalized Pregnant and Postpartum Women with Severe COVID-19: A Retrospective Cohort Study.
de Freitas Paganoti C, Alkmin da Costa R, Papageorghiou AT, da Silva Costa F, Quintana SM, Graziela de Godoi L, Adriana Jiménez Monroy N, Sacramento Rodrigues A, Pulcineli Vieira Francisco R. de Freitas Paganoti C, et al. Vaccines (Basel). 2022 May 10;10(5):749. doi: 10.3390/vaccines10050749. Vaccines (Basel). 2022. PMID: 35632505 Free PMC article.
The coronavirus disease 2019 (COVID-19) pandemic has had deleterious effects among the obstetric population. ...A total of 2284 pregnant and postpartum women hospitalized with severe COVID-19 were included. Those who did and who did not receive COVI …
The coronavirus disease 2019 (COVID-19) pandemic has had deleterious effects among the obstetric population. ...A total of 228 …
Protective ventilation and outcomes of critically ill patients with COVID-19: a cohort study.
Ferreira JC, Ho YL, Besen BAMP, Malbouisson LMS, Taniguchi LU, Mendes PV, Costa ELV, Park M, Daltro-Oliveira R, Roepke RML, Silva-Jr JM, Carmona MJC, Carvalho CRR; EPICCoV Study Group. Ferreira JC, et al. Ann Intensive Care. 2021 Jun 7;11(1):92. doi: 10.1186/s13613-021-00882-w. Ann Intensive Care. 2021. PMID: 34097145 Free PMC article.
BACKGROUND: Approximately 5% of COVID-19 patients develop respiratory failure and need ventilatory support, yet little is known about the impact of mechanical ventilation strategy in COVID-19. ...CONCLUSIONS: During the peak of the epidemic in Sao Paul …
BACKGROUND: Approximately 5% of COVID-19 patients develop respiratory failure and need ventilatory support, yet little is know …
Association between chemosensory impairment with neuropsychiatric morbidity in post-acute COVID-19 syndrome: results from a multidisciplinary cohort study.
Damiano RF, Neto DB, Oliveira JVR, Magalhães Santos J, Alves JVR, Guedes BF, Nitrini R, de Araújo AL, Oliveira M, Brunoni AR, Voegels RL, Bento RF, Busatto G, Miguel EC, Forlenza OV, de Rezende Pinna F; HCFMUSP COVID-19 study group. Damiano RF, et al. Eur Arch Psychiatry Clin Neurosci. 2023 Mar;273(2):325-333. doi: 10.1007/s00406-022-01427-3. Epub 2022 May 28. Eur Arch Psychiatry Clin Neurosci. 2023. PMID: 35633395 Free PMC article.
Preliminary methodologically limited studies suggested that taste and smell known as chemosensory impairments and neuropsychiatric symptoms are associated in post-COVID-19. The objective of this study is to evaluate whether chemosensory dysfunction and neurop …
Preliminary methodologically limited studies suggested that taste and smell known as chemosensory impairments and neuropsychiatric symptoms …
Vaccine effectiveness of ChAdOx1 nCoV-19 against COVID-19 in a socially vulnerable community in Rio de Janeiro, Brazil: a test-negative design study.
Ranzani OT, Silva AAB, Peres IT, Antunes BBP, Gonzaga-da-Silva TW, Soranz DR, Cerbino-Neto J, Hamacher S, Bozza FA. Ranzani OT, et al. Clin Microbiol Infect. 2022 May;28(5):736.e1-736.e4. doi: 10.1016/j.cmi.2022.01.032. Epub 2022 Feb 9. Clin Microbiol Infect. 2022. PMID: 35150884 Free PMC article.
METHODS: We conducted a test-negative study in the community Complexo da Mare, the largest group of slums (n = 16) in Rio de Janeiro, Brazil, from January 17, 2021 to November 27, 2021. ...Adjusted vaccine effectiveness against COVID-19 infection was 3 …
METHODS: We conducted a test-negative study in the community Complexo da Mare, the largest group of slums (n = 16) in Rio de J …
Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial.
Hess CN, Hsia J, Carroll IA, Nehler MR, Ruf W, Morrow DA, Nicolau JC, Berwanger O, Szarek M, Capell WH, Johri S, Pursley MS, Gupta R, Meehan PS, Franchi F, Effron MB, Marshall D, Graybill CA, Huebler SP, Keuer T, Bristow MR, Bonaca MP. Hess CN, et al. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1572-1582. doi: 10.1161/ATVBAHA.122.318748. Epub 2023 Jun 29. Arterioscler Thromb Vasc Biol. 2023. PMID: 37381988 Free PMC article. Clinical Trial.
BACKGROUND: Thrombo-inflammation is central to COVID-19-associated coagulopathy. TF (tissue factor), a driver of disordered coagulation and inflammation in viral infections, may be a therapeutic target in COVID-19. The safety and efficacy of the novel …
BACKGROUND: Thrombo-inflammation is central to COVID-19-associated coagulopathy. TF (tissue factor), a driver of disordered co …
101 results