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1991 1
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2004 3
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2006 3
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Page 1
Natural products in drug discovery: advances and opportunities.
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Atanasov AG, et al. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z. Epub 2021 Jan 28. Nat Rev Drug Discov. 2021. PMID: 33510482 Free PMC article. Review.
Dammarane-type triterpenoid saponins from Salvia russellii Benth.
Hafez Ghoran S, Firuzi O, Asadollahi M, Stuppner H, Alilou M, Jassbi AR. Hafez Ghoran S, et al. Phytochemistry. 2021 Apr;184:112653. doi: 10.1016/j.phytochem.2020.112653. Epub 2021 Jan 29. Phytochemistry. 2021. PMID: 33524860
The chemical structures of the aforementioned compounds were characterized, using detailed spectroscopic analyses, including high-resolution mass spectrometry and 1D and 2D NMR ((1)H-(1)H COSY, TOCSY, HSQC, HMBC and NOESY) spectroscopy as well as physicochemical pro …
The chemical structures of the aforementioned compounds were characterized, using detailed spectroscopic analyses, including high-resolution …
The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.
McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. McAlpine JB, et al. Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Nat Prod Rep. 2019. PMID: 30003207 Free PMC article. Review.
Differentiation between Cistus L. (Sub-) Species (Cistaceae) Using NMR Metabolic Fingerprinting.
Moosmang S, Sturm S, Novak J, Lukas B, Stuppner H. Moosmang S, et al. Planta Med. 2020 Oct;86(15):1148-1155. doi: 10.1055/a-1176-1937. Epub 2020 Jun 3. Planta Med. 2020. PMID: 32492718
Samples were extracted with buffered aqueous methanol and analysed with NMR. From the resulting 1D-(1)H-NOESY and J-Res profile spectra, marker signals or spectral regions for the individual (sub-) species were identified with multivariate statistical tools. ...
Samples were extracted with buffered aqueous methanol and analysed with NMR. From the resulting 1D-(1)H-NOESY and J-Res profile spect …
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.
Cytotoxic activities of hypocretenolides from Leontodon hispidus.
Zidorn C, Stuppner H, Tiefenthaler M, Konwalinka G. Zidorn C, et al. J Nat Prod. 1999 Jul;62(7):984-7. doi: 10.1021/np990058v. J Nat Prod. 1999. PMID: 10425121
In the present communication we report on the cytotoxic effects of three hypocretenolides (1-3) from Leontodon hispidus on: (a) eight solid-tumor cell lines (A431, HEP2, MCF7, OVCAR3, SK28, SK37, SW872, ZR75-1), tested by a (3)H-thymidine incorporation assay; (b) two diffe …
In the present communication we report on the cytotoxic effects of three hypocretenolides (1-3) from Leontodon hispidus on: (a) eight solid- …
Eudesmane derivatives from Hieracium intybaceum.
Grass S, Zidorn C, Ellmerer EP, Stuppner H. Grass S, et al. Chem Biodivers. 2004 Feb;1(2):353-60. doi: 10.1002/cbdv.200490031. Chem Biodivers. 2004. PMID: 17191853
Two new eudesmanolides, 4beta-H,3beta-(beta-D-glucopyranosyloxy)eudesma-1,11(13)-dien-12,6-olide (5a) and 3beta-D-glucopyranosyloxyeudesma-1,4(15),11(13)-trien-12,6-olide (5b), as well as two related, known compounds, tuberiferin (7a) and dehydrobrachylaenolide (7b), were …
Two new eudesmanolides, 4beta-H,3beta-(beta-D-glucopyranosyloxy)eudesma-1,11(13)-dien-12,6-olide (5a) and 3beta-D-glucopyranosyloxyeu …
Plumeridoid C from the Amazonian traditional medicinal plant Himatanthus sucuuba.
Waltenberger B, Rollinger JM, Griesser UJ, Stuppner H, Gelbrich T. Waltenberger B, et al. Acta Crystallogr C. 2011 Oct;67(Pt 10):o409-12. doi: 10.1107/S0108270111035761. Epub 2011 Sep 29. Acta Crystallogr C. 2011. PMID: 21979978 Free PMC article.
The stereochemistry of the iridoid plumeridoid C, C(15)H(18)O(7), was established by X-ray single-crystal structure analysis, giving (2'R,3R,4R,4aS,7aR)-methyl 3-hydroxy-4'-[(S)-1-hydroxyethyl]-5'-oxo-3,4,4a,7a-tetrahydro-1H,5'H-spiro[cyclopenta[c]pyran-7,2'-furan]- …
The stereochemistry of the iridoid plumeridoid C, C(15)H(18)O(7), was established by X-ray single-crystal structure analysis, giving …
40 results