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Structure of the human ClC-1 chloride channel.
Wang K, Preisler SS, Zhang L, Cui Y, Missel JW, Grønberg C, Gotfryd K, Lindahl E, Andersson M, Calloe K, Egea PF, Klaerke DA, Pusch M, Pedersen PA, Zhou ZH, Gourdon P. Wang K, et al. PLoS Biol. 2019 Apr 25;17(4):e3000218. doi: 10.1371/journal.pbio.3000218. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 31022181 Free PMC article.
Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine ClC-K and CLC transporters. The chloride conducting pathway exhibits distinct features, including a central glutamate residue ("fast g …
Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine C …
Rationalizing the management of pregnancies of unknown location: temporal and external validation of a risk prediction model on 1962 pregnancies.
Van Calster B, Abdallah Y, Guha S, Kirk E, Van Hoorde K, Condous G, Preisler J, Hoo W, Stalder C, Bottomley C, Timmerman D, Bourne T. Van Calster B, et al. Hum Reprod. 2013 Mar;28(3):609-16. doi: 10.1093/humrep/des440. Epub 2013 Jan 4. Hum Reprod. 2013. PMID: 23293216
M4 is a multinomial logistic regression model based on the serum human chorionic gonadotrophin (hCG) levels at presentation and 48 h later. PARTICIPANTS/MATERIALS, SETTING, METHODS: Temporal validation data from 1341 PULs collected at St George's Hospital in London were av …
M4 is a multinomial logistic regression model based on the serum human chorionic gonadotrophin (hCG) levels at presentation and 48 h …
Monovalent ions control proliferation of Ehrlich Lettre ascites cells.
Klausen TK, Preisler S, Pedersen SF, Hoffmann EK. Klausen TK, et al. Am J Physiol Cell Physiol. 2010 Sep;299(3):C714-25. doi: 10.1152/ajpcell.00445.2009. Epub 2010 Jun 30. Am J Physiol Cell Physiol. 2010. PMID: 20592244 Free article.
However, the mechanisms involved in modulation of proliferation by monovalent ions are poorly understood. Here, we investigated the role of K+, Na+, and Cl(-) ions for the proliferation of Ehrlich Lettre ascites (ELA) cells. ...In spectrofluorometric measurements with the …
However, the mechanisms involved in modulation of proliferation by monovalent ions are poorly understood. Here, we investigated the role of …