Validation of the use of dried blood spots in a chikungunya virus IgG serological assay.
Magalhaes T, Portilho MM, Moreira PSS, Marinho ML, Dias WP, Gonçalves NM, Rodrigues OAS, Montes J, Reis L, Jesus DF, Silva TO, Dultra LS, Nery JS, Ribeiro GS.
Magalhaes T, et al.
J Immunol Methods. 2023 Nov;522:113571. doi: 10.1016/j.jim.2023.113571. Epub 2023 Sep 22.
J Immunol Methods. 2023.
PMID: 37742825
The sensitivity and specificity of the CHIKV ELISA of DBS compared to sera were 100% (95% C.I.: 85.8-100%) and 100% (95% C.I.: 93-100%), respectively. In the linear regression analysis, a coefficient of determination (R(2)) value of 0.98 indicated the excellent perf …
The sensitivity and specificity of the CHIKV ELISA of DBS compared to sera were 100% (95% C.I.: 85.8-100%) and 100% (95% C.I.: …