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Showing results for gerhard koenig
Your search for Gerhard Kopeinig retrieved no results
Discovery and characterization of novel TRPML1 agonists.
Peng X, Holler CJ, Alves AF, Oliviera MG, Speake M, Pugliese A, Oskouei MR, de Freitas ID, Chen AY, Gallegos R, McTighe SM, Koenig G, Hurst RS, Blain JF, Lanter JC, Burnett DA. Peng X, et al. Among authors: koenig g. Bioorg Med Chem Lett. 2024 Jan 15;98:129595. doi: 10.1016/j.bmcl.2023.129595. Epub 2023 Dec 22. Bioorg Med Chem Lett. 2024. PMID: 38141860
Discovery of quinuclidine modulators of cellular progranulin.
Lanter JC, Chen AY, Williamson T, Koenig G, Blain JF, Burnett DA. Lanter JC, et al. Among authors: koenig g. Bioorg Med Chem Lett. 2021 Sep 1;47:128209. doi: 10.1016/j.bmcl.2021.128209. Epub 2021 Jun 18. Bioorg Med Chem Lett. 2021. PMID: 34153473
Discovery of oxazoline enhancers of cellular progranulin release.
Peng X, Lanter JC, Y-P Chen A, Brand MA, Wozniak MK, Hoekman S, Longin O, Regeling H, Zonneveld W, P L Bell R, Koenig G, Hurst RS, Blain JF, Burnett DA. Peng X, et al. Among authors: koenig g. Bioorg Med Chem Lett. 2023 Jan 15;80:129048. doi: 10.1016/j.bmcl.2022.129048. Epub 2022 Nov 8. Bioorg Med Chem Lett. 2023. PMID: 36368496
US immigration order strikes against biotech.
Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, M… See abstract for full author list ➔ Levin JM, et al. Among authors: koenig g. Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. Nat Biotechnol. 2017. PMID: 28267733 No abstract available.
Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator.
Bursavich MG, Harrison BA, Acharya R, Costa DE, Freeman EA, Hrdlicka LA, Jin H, Kapadnis S, Moffit JS, Murphy D, Nolan SJ, Patzke H, Tang C, Van Voorhies HE, Wen M, Koenig G, Blain JF, Burnett DA. Bursavich MG, et al. Among authors: koenig g. J Med Chem. 2021 Oct 14;64(19):14426-14447. doi: 10.1021/acs.jmedchem.1c00904. Epub 2021 Sep 22. J Med Chem. 2021. PMID: 34550687
BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines.
Blume T, Filser S, Jaworska A, Blain JF, Koenig G, Moschke K, Lichtenthaler SF, Herms J. Blume T, et al. Among authors: koenig g. Front Aging Neurosci. 2018 Jul 26;10:229. doi: 10.3389/fnagi.2018.00229. eCollection 2018. Front Aging Neurosci. 2018. PMID: 30093858 Free PMC article.
Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment.
Wu J, Shih HP, Vigont V, Hrdlicka L, Diggins L, Singh C, Mahoney M, Chesworth R, Shapiro G, Zimina O, Chen X, Wu Q, Glushankova L, Ahlijanian M, Koenig G, Mozhayeva GN, Kaznacheyeva E, Bezprozvanny I. Wu J, et al. Among authors: koenig g. Chem Biol. 2011 Jun 24;18(6):777-93. doi: 10.1016/j.chembiol.2011.04.012. Chem Biol. 2011. PMID: 21700213 Free PMC article.
Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial.
Ljubenkov PA, Edwards L, Iaccarino L, La Joie R, Rojas JC, Koestler M, Harris B, Boeve BF, Borroni B, van Swieten JC, Grossman M, Pasquier F, Frisoni GB, Mummery CJ, Vandenberghe R, Le Ber I, Hannequin D, McGinnis SM, Auriacombe S, Onofrj M, Goodman IJ, Riordan HJ, Wisniewski G, Hesterman J, Marek K, Haynes BA, Patzke H, Koenig G, Hilt D, Moebius H, Boxer AL. Ljubenkov PA, et al. Among authors: koenig g. JAMA Netw Open. 2021 Sep 1;4(9):e2125584. doi: 10.1001/jamanetworkopen.2021.25584. JAMA Netw Open. 2021. PMID: 34559230 Free PMC article. Clinical Trial.
22 results