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2021 6
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Page 1
Immune imprinting and next-generation coronavirus vaccines.
Huang CQ, Vishwanath S, Carnell GW, Chan ACY, Heeney JL. Huang CQ, et al. Nat Microbiol. 2023 Nov;8(11):1971-1985. doi: 10.1038/s41564-023-01505-9. Epub 2023 Nov 6. Nat Microbiol. 2023. PMID: 37932355 Review.
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity.
Stewart H, Lu Y, O'Keefe S, Valpadashi A, Cruz-Zaragoza LD, Michel HA, Nguyen SK, Carnell GW, Lukhovitskaya N, Milligan R, Adewusi Y, Jungreis I, Lulla V, Matthews DA, High S, Rehling P, Emmott E, Heeney JL, Davidson AD, Edgar JR, Smith GL, Firth AE. Stewart H, et al. Among authors: carnell gw. iScience. 2023 Sep 28;26(11):108080. doi: 10.1016/j.isci.2023.108080. eCollection 2023 Nov 17. iScience. 2023. PMID: 37860693 Free PMC article.
Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: carnell gw. EMBO Rep. 2023 Dec 6;24(12):e57224. doi: 10.15252/embr.202357224. Epub 2023 Oct 11. EMBO Rep. 2023. PMID: 37818801 Free PMC article.
AutoPlate: Rapid Dose-Response Curve Analysis for Biological Assays.
Palmer P, Del Rosario JMM, da Costa KAS, Carnell GW, Huang CQ, Heeney JL, Temperton NJ, Wells DA. Palmer P, et al. Among authors: carnell gw. Front Immunol. 2022 Feb 10;12:681636. doi: 10.3389/fimmu.2021.681636. eCollection 2021. Front Immunol. 2022. PMID: 35222351 Free PMC article.
Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: carnell gw. bioRxiv [Preprint]. 2022 Dec 22:2021.01.06.425396. doi: 10.1101/2021.01.06.425396. bioRxiv. 2022. PMID: 33442692 Free PMC article. Updated. Preprint.
SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses.
Carnell GW, Ciazynska KA, Wells DA, Xiong X, Aguinam ET, McLaughlin SH, Mallery D, Ebrahimi S, Ceron-Gutierrez L, Asbach B, Einhauser S, Wagner R, James LC, Doffinger R, Heeney JL, Briggs JAG. Carnell GW, et al. J Virol. 2021 Jul 12;95(15):e0020321. doi: 10.1128/JVI.00203-21. Epub 2021 Jul 12. J Virol. 2021. PMID: 33963055 Free PMC article.
Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses.
McNaughton AL, Paton RS, Edmans M, Youngs J, Wellens J, Phalora P, Fyfe A, Belij-Rammerstorfer S, Bolton JS, Ball J, Carnell GW, Dejnirattisai W, Dold C, Eyre DW, Hopkins P, Howarth A, Kooblall K, Klim H, Leaver S, Lee LN, López-Camacho C, Lumley SF, Macallan DC, Mentzer AJ, Provine NM, Ratcliff J, Slon-Compos J, Skelly D, Stolle L, Supasa P, Temperton N, Walker C, Wang B, Wyncoll D; Oxford Protective T Cell Immunology for COVID-19 (OPTIC) consortium; Scottish National Blood Transfusion Service (SNBTS) consortium; Simmonds P, Lambe T, Baillie JK, Semple MG, Openshaw PJ; International Severe Acute Respiratory and emerging Infection Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) investigators; Obolski U, Turner M, Carroll M, Mongkolsapaya J, Screaton G, Kennedy SH, Jarvis L, Barnes E, Dunachie S, Lourenço J, Matthews PC, Bicanic T, Klenerman P, Gupta S, Thompson CP. McNaughton AL, et al. Among authors: carnell gw. JCI Insight. 2022 Jul 8;7(13):e156372. doi: 10.1172/jci.insight.156372. JCI Insight. 2022. PMID: 35608920 Free PMC article.
SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress.
Scherer KM, Mascheroni L, Carnell GW, Wunderlich LCS, Makarchuk S, Brockhoff M, Mela I, Fernandez-Villegas A, Barysevich M, Stewart H, Suau Sans M, George CL, Lamb JR, Kaminski-Schierle GS, Heeney JL, Kaminski CF. Scherer KM, et al. Among authors: carnell gw. Sci Adv. 2022 Jan 7;8(1):eabl4895. doi: 10.1126/sciadv.abl4895. Epub 2022 Jan 7. Sci Adv. 2022. PMID: 34995113 Free PMC article.
22 results