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Page 1
Recent advances to accelerate purification process development: A review with a focus on vaccines.
J Chromatogr A. 2022 Aug 2;1676:463195. doi: 10.1016/j.chroma.2022.463195. Epub 2022 Jun 2.
J Chromatogr A. 2022.
PMID: 35749985
Free article.
Review.
Using artificial neural networks to accelerate flowsheet optimization for downstream process development.
Keulen D, van der Hagen E, Geldhof G, Le Bussy O, Pabst M, Ottens M.
Keulen D, et al. Among authors: geldhof g.
Biotechnol Bioeng. 2023 May 31. doi: 10.1002/bit.28454. Online ahead of print.
Biotechnol Bioeng. 2023.
PMID: 37256724
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Characterisation of the E. coli HMS174 and BLR host cell proteome to guide purification process development.
Disela R, Bussy OL, Geldhof G, Pabst M, Ottens M.
Disela R, et al. Among authors: geldhof g.
Biotechnol J. 2023 Sep;18(9):e2300068. doi: 10.1002/biot.202300068. Epub 2023 Jun 5.
Biotechnol J. 2023.
PMID: 37208824
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Predicting protein retention in ion-exchange chromatography using an open source QSPR workflow.
Neijenhuis T, Le Bussy O, Geldhof G, Klijn ME, Ottens M.
Neijenhuis T, et al. Among authors: geldhof g.
Biotechnol J. 2024 Mar;19(3):e2300708. doi: 10.1002/biot.202300708.
Biotechnol J. 2024.
PMID: 38479997
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Working within the Design Space: Do Our Static Process Characterization Methods Suffice?
von Stosch M, Schenkendorf R, Geldhof G, Varsakelis C, Mariti M, Dessoy S, Vandercammen A, Pysik A, Sanders M.
von Stosch M, et al. Among authors: geldhof g.
Pharmaceutics. 2020 Jun 17;12(6):562. doi: 10.3390/pharmaceutics12060562.
Pharmaceutics. 2020.
PMID: 32560435
Free PMC article.
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