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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 3
2007 1
2008 1
2009 3
2010 7
2011 11
2012 11
2013 15
2014 9
2015 16
2016 23
2017 29
2018 43
2019 56
2020 48
2021 54
2022 52
2023 57
2024 20

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417 results

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Page 1
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: chen g. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843 Free PMC article.
Dual base editor catalyzes both cytosine and adenine base conversions in human cells.
Zhang X, Zhu B, Chen L, Xie L, Yu W, Wang Y, Li L, Yin S, Yang L, Hu H, Han H, Li Y, Wang L, Chen G, Ma X, Geng H, Huang W, Pang X, Yang Z, Wu Y, Siwko S, Kurita R, Nakamura Y, Yang L, Liu M, Li D. Zhang X, et al. Among authors: chen g. Nat Biotechnol. 2020 Jul;38(7):856-860. doi: 10.1038/s41587-020-0527-y. Epub 2020 Jun 1. Nat Biotechnol. 2020. PMID: 32483363
Transcriptomics, proteomics, metabolomics and network pharmacology reveal molecular mechanisms of multi-targets effects of Shenxianshengmai improving human iPSC-CMs beating.
Hu Y, Chen L, Zhao S, Feng R, Cao X, Chen G, Zhao T, Zhang C, Fang Z, Guo Z, Yu X, Zhang Z, Abdurahman M, Hong H, He Y, Li H. Hu Y, et al. Among authors: chen g. Clin Transl Med. 2023 Jun;13(6):e1302. doi: 10.1002/ctm2.1302. Clin Transl Med. 2023. PMID: 37282796 Free PMC article. No abstract available.
Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity.
Long X, Zhang S, Wang Y, Chen J, Lu Y, Hou H, Lin B, Li X, Shen C, Yang R, Zhu H, Cui R, Cao D, Chen G, Wang D, Chen Y, Zhai S, Zeng Z, Wu S, Lou M, Chen J, Zou J, Zheng M, Qin J, Wang X. Long X, et al. Among authors: chen g. Nat Immunol. 2024 Mar;25(3):525-536. doi: 10.1038/s41590-024-01746-8. Epub 2024 Feb 14. Nat Immunol. 2024. PMID: 38356061
RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis.
Yue Z, Niu X, Yuan Z, Qin Q, Jiang W, He L, Gao J, Ding Y, Liu Y, Xu Z, Li Z, Yang Z, Li R, Xue X, Gao Y, Yue F, Zhang XH, Hu G, Wang Y, Li Y, Chen G, Siwko S, Gartland A, Wang N, Xiao J, Liu M, Luo J. Yue Z, et al. Among authors: chen g. J Clin Invest. 2022 Jan 18;132(2):e144579. doi: 10.1172/JCI144579. J Clin Invest. 2022. PMID: 34847079 Free PMC article.
Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial.
Sweeney C, Bracarda S, Sternberg CN, Chi KN, Olmos D, Sandhu S, Massard C, Matsubara N, Alekseev B, Parnis F, Atduev V, Buchschacher GL Jr, Gafanov R, Corrales L, Borre M, Stroyakovskiy D, Alves GV, Bournakis E, Puente J, Harle-Yge ML, Gallo J, Chen G, Hanover J, Wongchenko MJ, Garcia J, de Bono JS. Sweeney C, et al. Among authors: chen g. Lancet. 2021 Jul 10;398(10295):131-142. doi: 10.1016/S0140-6736(21)00580-8. Lancet. 2021. PMID: 34246347 Clinical Trial.
417 results