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Year Number of Results
2016 3
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2020 1
2021 2
2022 2
2024 0

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Page 1
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Costantino L, Ferrari S, Santucci M, Salo-Ahen OMH, Carosati E, Franchini S, Lauriola A, Pozzi C, Trande M, Gozzi G, Saxena P, Cannazza G, Losi L, Cardinale D, Venturelli A, Quotadamo A, Linciano P, Tagliazucchi L, Moschella MG, Guerrini R, Pacifico S, Luciani R, Genovese F, Henrich S, Alboni S, Santarem N, da Silva Cordeiro A, Giovannetti E, Peters GJ, Pinton P, Rimessi A, Cruciani G, Stroud RM, Wade RC, Mangani S, Marverti G, D'Arca D, Ponterini G, Costi MP. Costantino L, et al. Among authors: gozzi g. Elife. 2022 Dec 7;11:e73862. doi: 10.7554/eLife.73862. Elife. 2022. PMID: 36475542 Free PMC article.
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting.
Marverti G, Marraccini C, Martello A, D'Arca D, Pacifico S, Guerrini R, Spyrakis F, Gozzi G, Lauriola A, Santucci M, Cannazza G, Tagliazucchi L, Cazzato AS, Losi L, Ferrari S, Ponterini G, Costi MP. Marverti G, et al. Among authors: gozzi g. J Med Chem. 2021 Mar 25;64(6):3204-3221. doi: 10.1021/acs.jmedchem.0c02107. Epub 2021 Mar 12. J Med Chem. 2021. PMID: 33710891 Free PMC article.
The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines.
Marverti G, Gozzi G, Lauriola A, Ponterini G, Belluti S, Imbriano C, Costi MP, D'Arca D. Marverti G, et al. Among authors: gozzi g. Int J Mol Sci. 2019 Dec 4;20(24):6122. doi: 10.3390/ijms20246122. Int J Mol Sci. 2019. PMID: 31817267 Free PMC article.
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells.
Marverti G, Gozzi G, Maretti E, Lauriola A, Severi L, Sacchetti F, Losi L, Pacifico S, Ferrari S, Ponterini G, Leo E, Costi MP, D'Arca D. Marverti G, et al. Among authors: gozzi g. Int J Mol Sci. 2020 Jun 23;21(12):4452. doi: 10.3390/ijms21124452. Int J Mol Sci. 2020. PMID: 32585842 Free PMC article.
12 results