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The ellagitannin metabolite urolithin C is a glucose-dependent regulator of insulin secretion through activation of L-type calcium channels.
Bayle M, Neasta J, Dall'Asta M, Gautheron G, Virsolvy A, Quignard JF, Youl E, Magous R, Guichou JF, Crozier A, Del Rio D, Cros G, Oiry C. Bayle M, et al. Among authors: cros g. Br J Pharmacol. 2019 Oct;176(20):4065-4078. doi: 10.1111/bph.14821. Epub 2019 Oct 10. Br J Pharmacol. 2019. PMID: 31378934 Free PMC article.
Development and validation of a liquid chromatography-electrospray ionization-tandem mass spectrometry method for the determination of urolithin C in rat plasma and its application to a pharmacokinetic study.
Bayle M, Roques C, Marion B, Audran M, Oiry C, Bressolle-Gomeni FMM, Cros G. Bayle M, et al. Among authors: cros g. J Pharm Biomed Anal. 2016 Nov 30;131:33-39. doi: 10.1016/j.jpba.2016.07.046. Epub 2016 Aug 5. J Pharm Biomed Anal. 2016. PMID: 27521987
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