Gérald Cruciani - Search Results

Year	Number of Results
2020	4
2021	3
2022	1
2024	0

1

Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment.

Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabaté-Soler S, Rosety I, Griesbeck A, Skwirblies F, Zaffaroni G, Smits LM, Su J, Arias-Fuenzalida J, Walter J, Gomez-Giro G, Monzel AS, Qing X, Vitali A, Cruciani G, Boussaad I, Brunelli F, Jäger C, Rakovic A, Li W, Yuan L, Berger E, Arena G, Bolognin S, Schmidt R, Schröder C, Antony PMA, Klein C, Krüger R, Seibler P, Schwamborn JC. Jarazo J, et al. Among authors: cruciani g. Mov Disord. 2022 Jan;37(1):80-94. doi: 10.1002/mds.28810. Epub 2021 Oct 12. Mov Disord. 2022. PMID: 34637165 Free PMC article.

2

Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function.

Barbuti PA, Ohnmacht J, Santos BFR, Antony PM, Massart F, Cruciani G, Dording CM, Pavelka L, Casadei N, Kwon YJ, Krüger R. Barbuti PA, et al. Among authors: cruciani g. Sci Rep. 2021 Nov 9;11(1):21946. doi: 10.1038/s41598-021-01505-x. Sci Rep. 2021. PMID: 34754035 Free PMC article.

3

A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.

Boussaad I, Obermaier CD, Hanss Z, Bobbili DR, Bolognin S, Glaab E, Wołyńska K, Weisschuh N, De Conti L, May C, Giesert F, Grossmann D, Lambert A, Kirchen S, Biryukov M, Burbulla LF, Massart F, Bohler J, Cruciani G, Schmid B, Kurz-Drexler A, May P, Duga S, Klein C, Schwamborn JC, Marcus K, Woitalla D, Vogt Weisenhorn DM, Wurst W, Baralle M, Krainc D, Gasser T, Wissinger B, Krüger R. Boussaad I, et al. Among authors: cruciani g. Sci Transl Med. 2020 Sep 9;12(560):eaau3960. doi: 10.1126/scitranslmed.aau3960. Sci Transl Med. 2020. PMID: 32908004

4

Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening.

Boussaad I, Cruciani G, Bolognin S, Antony P, Dording CM, Kwon YJ, Heutink P, Fava E, Schwamborn JC, Krüger R. Boussaad I, et al. Among authors: cruciani g. Sci Rep. 2021 Jan 14;11(1):1439. doi: 10.1038/s41598-021-81129-3. Sci Rep. 2021. PMID: 33446877 Free PMC article.

5

Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson's Disease Point Mutation A30P.

Barbuti P, Antony P, Santos B, Massart F, Cruciani G, Dording C, Arias J, Schwamborn J, Krüger R. Barbuti P, et al. Among authors: cruciani g. Cells. 2020 Sep 10;9(9):2065. doi: 10.3390/cells9092065. Cells. 2020. PMID: 32927687 Free PMC article.

6

Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA.

Barbuti PA, Santos BFR, Dording CM, Cruciani G, Massart F, Hummel A, Krüger R. Barbuti PA, et al. Among authors: cruciani g. Stem Cell Res. 2020 Oct;48:101951. doi: 10.1016/j.scr.2020.101951. Epub 2020 Aug 8. Stem Cell Res. 2020. PMID: 32798915 Free article.

7

Induced pluripotent stem cell line (LCSBi001-A) derived from a patient with Parkinson's disease carrying the p.D620N mutation in VPS35.

Larsen SB, Hanss Z, Cruciani G, Massart F, Barbuti PA, Mellick G, Krüger R. Larsen SB, et al. Among authors: cruciani g. Stem Cell Res. 2020 May;45:101776. doi: 10.1016/j.scr.2020.101776. Epub 2020 Apr 4. Stem Cell Res. 2020. PMID: 32387898 Free article.

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