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Page 1
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma.
Wartewig T, Daniels J, Schulz M, Hameister E, Joshi A, Park J, Morrish E, Venkatasubramani AV, Cernilogar FM, van Heijster FHA, Hundshammer C, Schneider H, Konstantinidis F, Gabler JV, Klement C, Kurniawan H, Law C, Lee Y, Choi S, Guitart J, Forne I, Giustinani J, Müschen M, Jain S, Weinstock DM, Rad R, Ortonne N, Schilling F, Schotta G, Imhof A, Brenner D, Choi J, Ruland J. Wartewig T, et al. Among authors: van heijster fha. Nat Cancer. 2023 Oct;4(10):1508-1525. doi: 10.1038/s43018-023-00635-7. Epub 2023 Sep 18. Nat Cancer. 2023. PMID: 37723306 Free PMC article.
Parahydrogen-Polarized [1-13 C]Pyruvate for Reliable and Fast Preclinical Metabolic Magnetic Resonance Imaging.
Nagel L, Gierse M, Gottwald W, Ahmadova Z, Grashei M, Wolff P, Josten F, Karaali S, Müller CA, Lucas S, Scheuer J, Müller C, Blanchard J, Topping GJ, Wendlinger A, Setzer N, Sühnel S, Handwerker J, Vassiliou C, van Heijster FHA, Knecht S, Keim M, Schilling F, Schwartz I. Nagel L, et al. Among authors: van heijster fha. Adv Sci (Weinh). 2023 Oct;10(30):e2303441. doi: 10.1002/advs.202303441. Epub 2023 Aug 16. Adv Sci (Weinh). 2023. PMID: 37587776 Free PMC article.
Lithium isotopes differentially modify mitochondrial amorphous calcium phosphate cluster size distribution and calcium capacity.
Deline ML, Straub J, Patel M, Subba P, Grashei M, van Heijster FHA, Pirkwieser P, Somoza V, Livingstone JD, Beazely M, Kendall B, Gingras MJP, Leonenko Z, Höschen C, Harrington G, Kuellmer K, Bian W, Schilling F, Fisher MPA, Helgeson ME, Fromme T. Deline ML, et al. Among authors: van heijster fha. Front Physiol. 2023 Sep 15;14:1200119. doi: 10.3389/fphys.2023.1200119. eCollection 2023. Front Physiol. 2023. PMID: 37781224 Free PMC article.
Spectrally selective bSSFP using off-resonant RF excitations permits high spatiotemporal resolution 3D metabolic imaging of hyperpolarized [1-13 C]Pyruvate-to-[1-13 C]lactate conversion.
Skinner JG, Topping GJ, Nagel L, Heid I, Hundshammer C, Grashei M, van Heijster FHA, Braren R, Schilling F. Skinner JG, et al. Among authors: van heijster fha. Magn Reson Med. 2023 Sep;90(3):894-909. doi: 10.1002/mrm.29676. Epub 2023 Apr 24. Magn Reson Med. 2023. PMID: 37093981
Pyruvate-lactate exchange and glucose uptake in human prostate cancer cell models. A study in xenografts and suspensions by hyperpolarized [1-13 C]pyruvate MRS and [18 F]FDG-PET.
van Heijster FHA, Heskamp S, Breukels V, Veltien A, Franssen GM, Jansen KCFJ, Boerman OC, Schalken JA, Scheenen TWJ, Heerschap A. van Heijster FHA, et al. NMR Biomed. 2020 Oct;33(10):e4362. doi: 10.1002/nbm.4362. Epub 2020 Jul 14. NMR Biomed. 2020. PMID: 32662543 Free PMC article.