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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.
Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A. Rodríguez-Nuevo A, et al. Among authors: diaz saez f. EMBO J. 2018 May 15;37(10):e96553. doi: 10.15252/embj.201796553. Epub 2018 Apr 9. EMBO J. 2018. PMID: 29632021 Free PMC article.
Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells.
Martínez C, Latorre J, Ortega F, Arnoriaga-Rodríguez M, Lluch A, Oliveras-Cañellas N, Díaz-Sáez F, Aragonés J, Camps M, Gumà A, Ricart W, Fernández-Real JM, Moreno-Navarrete JM. Martínez C, et al. Among authors: diaz saez f. Front Physiol. 2022 Sep 15;13:950791. doi: 10.3389/fphys.2022.950791. eCollection 2022. Front Physiol. 2022. PMID: 36187779 Free PMC article.
Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles.
Díaz-Sáez F, Blanco-Sinfreu C, Archilla-Ortega A, Sebastian D, Romero M, Hernández-Alvarez MI, Mora S, Testar X, Ricart W, Fernández-Real JM, Moreno-Navarrete JM, Aragonés J, Camps M, Zorzano A, Gumà A. Díaz-Sáez F, et al. Int J Mol Sci. 2021 Nov 30;22(23):12960. doi: 10.3390/ijms222312960. Int J Mol Sci. 2021. PMID: 34884763 Free PMC article.
Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue.
Comas F, Martínez C, Sabater M, Ortega F, Latorre J, Díaz-Sáez F, Aragonés J, Camps M, Gumà A, Ricart W, Fernández-Real JM, Moreno-Navarrete JM. Comas F, et al. Among authors: diaz saez f. Front Physiol. 2019 Jan 31;10:39. doi: 10.3389/fphys.2019.00039. eCollection 2019. Front Physiol. 2019. PMID: 30766490 Free PMC article.