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Subclones with variants of uncertain clinical significance might contribute to ineffective hemopoiesis and leukemia predisposition.
Giudice V, Serio B, Errichiello S, Ferrara I, Galdiero A, Bertolini A, Visconti R, De Novellis D, Guariglia R, Luponio S, Morini D, Della Corte AM, Sessa AM, Verdesca F, Langella M, Izzo B, Selleri C. Giudice V, et al. Among authors: verdesca f. Eur J Haematol. 2023 Nov;111(5):729-741. doi: 10.1111/ejh.14069. Epub 2023 Jul 27. Eur J Haematol. 2023. PMID: 37501402
Clinical efficacy of azacytidine and venetoclax and prognostic impact of Tim-3 and galectin-9 in acute myeloid leukemia and high-risk myelodysplastic syndromes: A single-center real-life experience.
Giudice V, Serio B, Ferrara I, Manzo P, Gorrese M, Pepe R, Bertolini A, D'Alto F, Verdesca F, Langella M, Filippelli A, Selleri C. Giudice V, et al. Among authors: verdesca f. Front Pharmacol. 2022 Dec 21;13:1052060. doi: 10.3389/fphar.2022.1052060. eCollection 2022. Front Pharmacol. 2022. PMID: 36618908 Free PMC article.
c-Kit M541L variant is related to ineffective hemopoiesis predisposing to clonal evolution in 3D in vitro biomimetic co-culture model of bone marrow niche.
Manzo P, Scala P, Giudice V, Gorrese M, Bertolini A, Morini D, D'Alto F, Pepe R, Pedicini A, Izzo B, Verdesca F, Langella M, Serio B, Della Porta G, Selleri C. Manzo P, et al. Among authors: verdesca f. Heliyon. 2022 Dec 1;8(12):e11998. doi: 10.1016/j.heliyon.2022.e11998. eCollection 2022 Dec. Heliyon. 2022. PMID: 36478848 Free PMC article.