François Vallée - Search Results

Year	Number of Results
2001	1
2002	1
2003	1
2004	2
2005	2
2006	1
2007	1
2011	2
2013	1
2014	1
2015	2
2016	4
2018	1
2019	3
2020	1
2021	1
2022	2
2023	1
2024	0

1

Collecting New Peak and Intermediate Infliximab Levels to Predict Remission in Inflammatory Bowel Diseases.

Liefferinckx C, Bottieau J, Toubeau JF, Thomas D, Rahier JF, Louis E, Baert F, Dewint P, Pouillon L, Lambrecht G, Vallée F, Vermeire S, Bossuyt P, Franchimont D. Liefferinckx C, et al. Among authors: vallee f. Inflamm Bowel Dis. 2022 Feb 1;28(2):208-217. doi: 10.1093/ibd/izab042. Inflamm Bowel Dis. 2022. PMID: 33783494

2

Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations.

Wolf S, Amaral M, Lowinski M, Vallée F, Musil D, Güldenhaupt J, Dreyer MK, Bomke J, Frech M, Schlitter J, Gerwert K. Wolf S, et al. Among authors: vallee f. J Chem Inf Model. 2019 Dec 23;59(12):5135-5147. doi: 10.1021/acs.jcim.9b00592. Epub 2019 Nov 22. J Chem Inf Model. 2019. PMID: 31697501

3

New approach to determine the healthy immune variations by combining clustering methods.

Liefferinckx C, De Grève Z, Toubeau JF, Perée H, Quertinmont E, Tafciu V, Minsart C, Rahmouni S, Georges M, Vallée F, Franchimont D. Liefferinckx C, et al. Among authors: vallee f. Sci Rep. 2021 Apr 26;11(1):8917. doi: 10.1038/s41598-021-88272-x. Sci Rep. 2021. PMID: 33903641 Free PMC article. Clinical Trial.

4

An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery.

Linke P, Amaning K, Maschberger M, Vallee F, Steier V, Baaske P, Duhr S, Breitsprecher D, Rak A. Linke P, et al. Among authors: vallee f. J Biomol Screen. 2016 Apr;21(4):414-21. doi: 10.1177/1087057115618347. Epub 2015 Dec 2. J Biomol Screen. 2016. PMID: 26637553 Free PMC article.

5

Predictive models assessing the response to ustekinumab highlight the value of therapeutic drug monitoring in Crohn's disease.

Liefferinckx C, Hubert A, Thomas D, Bottieau J, Minsart C, Cremer A, Amininejad L, Vallée F, Toubeau JF, Franchimont D. Liefferinckx C, et al. Among authors: vallee f. Dig Liver Dis. 2023 Mar;55(3):366-372. doi: 10.1016/j.dld.2022.07.015. Epub 2022 Aug 14. Dig Liver Dis. 2023. PMID: 35977875

6

Estimation of Drug-Target Residence Times by τ-Random Acceleration Molecular Dynamics Simulations.

Kokh DB, Amaral M, Bomke J, Grädler U, Musil D, Buchstaller HP, Dreyer MK, Frech M, Lowinski M, Vallee F, Bianciotto M, Rak A, Wade RC. Kokh DB, et al. Among authors: vallee f. J Chem Theory Comput. 2018 Jul 10;14(7):3859-3869. doi: 10.1021/acs.jctc.8b00230. Epub 2018 Jun 4. J Chem Theory Comput. 2018. PMID: 29768913 Free article.

7

Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer.

El-Ahmad Y, Tabart M, Halley F, Certal V, Thompson F, Filoche-Rommé B, Gruss-Leleu F, Muller C, Brollo M, Fabien L, Loyau V, Bertin L, Richepin P, Pilorge F, Desmazeau P, Girardet C, Beccari S, Louboutin A, Lebourg G, Le-Roux J, Terrier C, Vallée F, Steier V, Mathieu M, Rak A, Abecassis PY, Vicat P, Benard T, Bouaboula M, Sun F, Shomali M, Hebert A, Levit M, Cheng H, Courjaud A, Ginesty C, Perrault C, Garcia-Echeverria C, McCort G, Schio L. El-Ahmad Y, et al. Among authors: vallee f. J Med Chem. 2020 Jan 23;63(2):512-528. doi: 10.1021/acs.jmedchem.9b01293. Epub 2019 Nov 27. J Med Chem. 2020. PMID: 31721572

8

CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.

Steinmetz A, Vallée F, Beil C, Lange C, Baurin N, Beninga J, Capdevila C, Corvey C, Dupuy A, Ferrari P, Rak A, Wonerow P, Kruip J, Mikol V, Rao E. Steinmetz A, et al. Among authors: vallee f. MAbs. 2016 Jul;8(5):867-78. doi: 10.1080/19420862.2016.1162932. Epub 2016 Mar 16. MAbs. 2016. PMID: 26984268 Free PMC article.

9

Fast NMR Methods for Measuring in the Direct and/or Competition Mode the Dissociation Constants of Chemical Fragments Interacting with a Receptor.

Dalvit C, Parent A, Vallée F, Mathieu M, Rak A. Dalvit C, et al. Among authors: vallee f. ChemMedChem. 2019 Jun 5;14(11):1115-1127. doi: 10.1002/cmdc.201900152. Epub 2019 May 14. ChemMedChem. 2019. PMID: 30925009

10

Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).

Ugolini A, Kenigsberg M, Rak A, Vallée F, Houtmann J, Lowinski M, Capdevila C, Khider J, Albert E, Martinet N, Nemecek C, Grapinet S, Bacqué E, Roesner M, Delaisi C, Calvet L, Bonche F, Semiond D, Egile C, Goulaouic H, Schio L. Ugolini A, et al. Among authors: vallee f. J Med Chem. 2016 Aug 11;59(15):7066-74. doi: 10.1021/acs.jmedchem.6b00280. Epub 2016 Jul 13. J Med Chem. 2016. PMID: 27355974

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