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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 1
2008 1
2009 1
2010 1
2011 2
2012 6
2013 1
2014 4
2015 1
2016 6
2017 7
2018 7
2019 6
2020 7
2021 12
2022 9
2023 10
2024 2

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81 results

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Page 1
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
Marquardt V, Theruvath J, Pauck D, Picard D, Qin N, Blümel L, Maue M, Bartl J, Ahmadov U, Langini M, Meyer FD, Cole A, Cruz-Cruz J, Graef CM, Wölfl M, Milde T, Witt O, Erdreich-Epstein A, Leprivier G, Kahlert U, Stefanski A, Stühler K, Keir ST, Bigner DD, Hauer J, Beez T, Knobbe-Thomsen CB, Fischer U, Felsberg J, Hansen FK, Vibhakar R, Venkatraman S, Cheshier SH, Reifenberger G, Borkhardt A, Kurz T, Remke M, Mitra S. Marquardt V, et al. Among authors: hansen fk. J Immunother Cancer. 2023 Jan;11(1):e005871. doi: 10.1136/jitc-2022-005871. J Immunother Cancer. 2023. PMID: 36639156 Free PMC article.
Development of the first geldanamycin-based HSP90 degraders.
Wurnig S, Vogt M, Hogenkamp J, Dienstbier N, Borkhardt A, Bhatia S, Hansen FK. Wurnig S, et al. Among authors: hansen fk. Front Chem. 2023 Jun 28;11:1219883. doi: 10.3389/fchem.2023.1219883. eCollection 2023. Front Chem. 2023. PMID: 37448856 Free PMC article.
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
Sinatra L, Vogelmann A, Friedrich F, Tararina MA, Neuwirt E, Colcerasa A, König P, Toy L, Yesiloglu TZ, Hilscher S, Gaitzsch L, Papenkordt N, Zhai S, Zhang L, Romier C, Einsle O, Sippl W, Schutkowski M, Gross O, Bendas G, Christianson DW, Hansen FK, Jung M, Schiedel M. Sinatra L, et al. Among authors: hansen fk. J Med Chem. 2023 Nov 9;66(21):14787-14814. doi: 10.1021/acs.jmedchem.3c01385. Epub 2023 Oct 30. J Med Chem. 2023. PMID: 37902787 Free PMC article.
Development of the first non-hydroxamate selective HDAC6 degraders.
Keuler T, König B, Bückreiß N, Kraft FB, König P, Schäker-Hübner L, Steinebach C, Bendas G, Gütschow M, Hansen FK. Keuler T, et al. Among authors: hansen fk. Chem Commun (Camb). 2022 Oct 4;58(79):11087-11090. doi: 10.1039/d2cc03712b. Chem Commun (Camb). 2022. PMID: 36098075
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.
Steinebach C, Bricelj A, Murgai A, Sosič I, Bischof L, Ng YLD, Heim C, Maiwald S, Proj M, Voget R, Feller F, Košmrlj J, Sapozhnikova V, Schmidt A, Zuleeg MR, Lemnitzer P, Mertins P, Hansen FK, Gütschow M, Krönke J, Hartmann MD. Steinebach C, et al. Among authors: hansen fk. J Med Chem. 2023 Nov 9;66(21):14513-14543. doi: 10.1021/acs.jmedchem.3c00851. Epub 2023 Oct 30. J Med Chem. 2023. PMID: 37902300 Free PMC article.
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science.
Müller CE, Hansen FK, Gütschow M, Lindsley CW, Liotta D. Müller CE, et al. Among authors: hansen fk. ACS Med Chem Lett. 2021 Sep 30;12(10):1508-1509. doi: 10.1021/acsmedchemlett.1c00476. eCollection 2021 Oct 14. ACS Med Chem Lett. 2021. PMID: 34676023 Free PMC article. No abstract available.
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science.
Müller CE, Hansen FK, Gütschow M, Lindsley CW, Liotta D. Müller CE, et al. Among authors: hansen fk. ACS Pharmacol Transl Sci. 2021 Sep 30;4(6):1712-1713. doi: 10.1021/acsptsci.1c00208. eCollection 2021 Dec 10. ACS Pharmacol Transl Sci. 2021. PMID: 34927004 Free PMC article. No abstract available.
81 results