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2002 3
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Showing results for fengling li
Search for Fenling Li instead (2 results)
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2.
Hanley RP, Nie DY, Tabor JR, Li F, Sobh A, Xu C, Barker NK, Dilworth D, Hajian T, Gibson E, Szewczyk MM, Brown PJ, Barsyte-Lovejoy D, Herring LE, Wang GG, Licht JD, Vedadi M, Arrowsmith CH, James LI. Hanley RP, et al. Among authors: li f. J Am Chem Soc. 2023 Apr 12;145(14):8176-8188. doi: 10.1021/jacs.3c01421. Epub 2023 Mar 28. J Am Chem Soc. 2023. PMID: 36976643
Chemical probes for protein arginine methyltransferases.
Li ASM, Li F, Eram MS, Bolotokova A, Dela Seña CC, Vedadi M. Li ASM, et al. Among authors: li f. Methods. 2020 Mar 15;175:30-43. doi: 10.1016/j.ymeth.2019.11.017. Epub 2019 Dec 3. Methods. 2020. PMID: 31809836 Review.
Improved green and red GRAB sensors for monitoring dopaminergic activity in vivo.
Zhuo Y, Luo B, Yi X, Dong H, Miao X, Wan J, Williams JT, Campbell MG, Cai R, Qian T, Li F, Weber SJ, Wang L, Li B, Wei Y, Li G, Wang H, Zheng Y, Zhao Y, Wolf ME, Zhu Y, Watabe-Uchida M, Li Y. Zhuo Y, et al. Among authors: li f. Nat Methods. 2023 Nov 30. doi: 10.1038/s41592-023-02100-w. Online ahead of print. Nat Methods. 2023. PMID: 38036855
Recruitment of FBXO22 for Targeted Degradation of NSD2.
Nie DY, Tabor JR, Li J, Kutera M, St-Germain J, Hanley RP, Wolf E, Paulakonis E, Kenney TMG, Duan S, Shrestha S, Owens DDG, Pon A, Szewczyk M, Lamberto AJ, Menes M, Li F, Barsyte-Lovejoy D, Brown NG, Barsotti AM, Stamford AW, Collins JL, Wilson DJ, Raught B, Licht JD, James LI, Arrowsmith CH. Nie DY, et al. Among authors: li f. bioRxiv [Preprint]. 2023 Nov 30:2023.11.01.564830. doi: 10.1101/2023.11.01.564830. bioRxiv. 2023. PMID: 37961297 Free PMC article. Preprint.
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
Dilworth D, Hanley RP, Ferreira de Freitas R, Allali-Hassani A, Zhou M, Mehta N, Marunde MR, Ackloo S, Carvalho Machado RA, Khalili Yazdi A, Owens DDG, Vu V, Nie DY, Alqazzaz M, Marcon E, Li F, Chau I, Bolotokova A, Qin S, Lei M, Liu Y, Szewczyk MM, Dong A, Kazemzadeh S, Abramyan T, Popova IK, Hall NW, Meiners MJ, Cheek MA, Gibson E, Kireev D, Greenblatt JF, Keogh MC, Min J, Brown PJ, Vedadi M, Arrowsmith CH, Barsyte-Lovejoy D, James LI, Schapira M. Dilworth D, et al. Among authors: li f. Nat Chem Biol. 2022 Jan;18(1):56-63. doi: 10.1038/s41589-021-00898-0. Epub 2021 Nov 15. Nat Chem Biol. 2022. PMID: 34782742 Free PMC article.
A germ-free humanized mouse model shows the contribution of resident microbiota to human-specific pathogen infection.
Wahl A, Yao W, Liao B, Chateau M, Richardson C, Ling L, Franks A, Senthil K, Doyon G, Li F, Frost J, Whitehurst CB, Pagano JS, Fletcher CA, Azcarate-Peril MA, Hudgens MG, Rogala AR, Tucker JD, McGowan I, Sartor RB, Garcia JV. Wahl A, et al. Among authors: li f. Nat Biotechnol. 2023 Aug 10. doi: 10.1038/s41587-023-01906-5. Online ahead of print. Nat Biotechnol. 2023. PMID: 37563299
Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase.
Singh I, Li F, Fink EA, Chau I, Li A, Rodriguez-Hernández A, Glenn I, Zapatero-Belinchón FJ, Rodriguez ML, Devkota K, Deng Z, White K, Wan X, Tolmachova NA, Moroz YS, Kaniskan HÜ, Ott M, García-Sastre A, Jin J, Fujimori DG, Irwin JJ, Vedadi M, Shoichet BK. Singh I, et al. Among authors: li f. J Med Chem. 2023 Jun 22;66(12):7785-7803. doi: 10.1021/acs.jmedchem.2c02120. Epub 2023 Jun 9. J Med Chem. 2023. PMID: 37294077
Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
Kimani SW, Owen J, Green SR, Li F, Li Y, Dong A, Brown PJ, Ackloo S, Kuter D, Yang C, MacAskill M, MacKinnon SS, Arrowsmith CH, Schapira M, Shahani V, Halabelian L. Kimani SW, et al. Among authors: li f. J Chem Inf Model. 2023 Jul 10;63(13):4070-4078. doi: 10.1021/acs.jcim.3c00082. Epub 2023 Jun 23. J Chem Inf Model. 2023. PMID: 37350740 Free article.
Reference compounds for characterizing cellular injury in high-content cellular morphology assays.
Dahlin JL, Hua BK, Zucconi BE, Nelson SD Jr, Singh S, Carpenter AE, Shrimp JH, Lima-Fernandes E, Wawer MJ, Chung LPW, Agrawal A, O'Reilly M, Barsyte-Lovejoy D, Szewczyk M, Li F, Lak P, Cuellar M, Cole PA, Meier JL, Thomas T, Baell JB, Brown PJ, Walters MA, Clemons PA, Schreiber SL, Wagner BK. Dahlin JL, et al. Among authors: li f. Nat Commun. 2023 Mar 13;14(1):1364. doi: 10.1038/s41467-023-36829-x. Nat Commun. 2023. PMID: 36914634 Free PMC article.
199 results