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Page 1
Rare genetic variant burden in DPYD predicts severe fluoropyrimidine-related toxicity risk.
De Mattia E, Silvestri M, Polesel J, Ecca F, Mezzalira S, Scarabel L, Zhou Y, Roncato R, Lauschke VM, Calza S, Spina M, Puglisi F, Toffoli G, Cecchin E. De Mattia E, et al. Among authors: ecca f. Biomed Pharmacother. 2022 Oct;154:113644. doi: 10.1016/j.biopha.2022.113644. Epub 2022 Sep 2. Biomed Pharmacother. 2022. PMID: 36063648 Free PMC article.
Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects.
Russo Spena C, De Stefano L, Poli G, Granchi C, El Boustani M, Ecca F, Grassi G, Grassi M, Canzonieri V, Giordano A, Tuccinardi T, Caligiuri I, Rizzolio F. Russo Spena C, et al. Among authors: ecca f. J Cell Physiol. 2019 Sep;234(9):15708-15716. doi: 10.1002/jcp.28224. Epub 2019 Jan 29. J Cell Physiol. 2019. PMID: 30697729
The Genotype for DPYD Risk Variants in Patients With Colorectal Cancer and the Related Toxicity Management Costs in Clinical Practice.
Toffoli G, Innocenti F, Polesel J, De Mattia E, Sartor F, Dalle Fratte C, Ecca F, Dreussi E, Palazzari E, Guardascione M, Buonadonna A, Foltran L, Garziera M, Bignucolo A, Nobili S, Mini E, Favaretto A, Berretta M, D'Andrea M, De Paoli A, Roncato R, Cecchin E. Toffoli G, et al. Among authors: ecca f. Clin Pharmacol Ther. 2019 Apr;105(4):994-1002. doi: 10.1002/cpt.1257. Epub 2018 Nov 22. Clin Pharmacol Ther. 2019. PMID: 30339275
Estimating the Effectiveness of DPYD Genotyping in Italian Individuals Suffering from Cancer Based on the Cost of Chemotherapy-Induced Toxicity.
Fragoulakis V, Roncato R, Fratte CD, Ecca F, Bartsakoulia M, Innocenti F, Toffoli G, Cecchin E, Patrinos GP, Mitropoulou C. Fragoulakis V, et al. Among authors: ecca f. Am J Hum Genet. 2019 Jun 6;104(6):1158-1168. doi: 10.1016/j.ajhg.2019.04.017. Epub 2019 May 30. Am J Hum Genet. 2019. PMID: 31155283 Free PMC article.