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Page 1
Antitumor activity of novel POLA1-HDAC11 dual inhibitors.
Dallavalle S, Musso L, Cincinelli R, Darwiche N, Gervasoni S, Vistoli G, Guglielmi MB, La Porta I, Pizzulo M, Modica E, Prosperi F, Signorino G, Colelli F, Cardile F, Fucci A, D'Andrea EL, Riccio A, Pisano C. Dallavalle S, et al. Among authors: colelli f. Eur J Med Chem. 2022 Jan 15;228:113971. doi: 10.1016/j.ejmech.2021.113971. Epub 2021 Nov 3. Eur J Med Chem. 2022. PMID: 34772529
The AKT1E17K Allele Promotes Breast Cancer in Mice.
Malanga D, Laudanna C, Mirante T, Colelli F, Migliozzi S, Zoppoli P, Santamaria G, Roberto L, De Marco C, Scarfò M, Montanaro D, Paciello O, Papparella S, Mignogna C, Baldi A, Viglietto G. Malanga D, et al. Among authors: colelli f. Cancers (Basel). 2022 May 26;14(11):2645. doi: 10.3390/cancers14112645. Cancers (Basel). 2022. PMID: 35681625 Free PMC article.
Novel adamantyl retinoid-related molecules with POLA1 inhibitory activity.
Cincinelli R, Musso L, Guglielmi MB, La Porta I, Fucci A, Luca D'Andrea E, Cardile F, Colelli F, Signorino G, Darwiche N, Gervasoni S, Vistoli G, Pisano C, Dallavalle S. Cincinelli R, et al. Among authors: colelli f. Bioorg Chem. 2020 Nov;104:104253. doi: 10.1016/j.bioorg.2020.104253. Epub 2020 Sep 2. Bioorg Chem. 2020. PMID: 32920362
Hybrid topoisomerase I and HDAC inhibitors as dual action anticancer agents.
Cincinelli R, Musso L, Artali R, Guglielmi MB, La Porta I, Melito C, Colelli F, Cardile F, Signorino G, Fucci A, Frusciante M, Pisano C, Dallavalle S. Cincinelli R, et al. Among authors: colelli f. PLoS One. 2018 Oct 9;13(10):e0205018. doi: 10.1371/journal.pone.0205018. eCollection 2018. PLoS One. 2018. PMID: 30300374 Free PMC article.
The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells.
Malanga D, De Marco C, Guerriero I, Colelli F, Rinaldo N, Scrima M, Mirante T, De Vitis C, Zoppoli P, Ceccarelli M, Riccardi M, Ravo M, Weisz A, Federico A, Franco R, Rocco G, Mancini R, Rizzuto A, Gulletta E, Ciliberto G, Viglietto G. Malanga D, et al. Among authors: colelli f. Oncotarget. 2015 Dec 15;6(40):42667-86. doi: 10.18632/oncotarget.5626. Oncotarget. 2015. PMID: 26486080 Free PMC article.
AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.
Malanga D, Belmonte S, Colelli F, Scarfò M, De Marco C, Oliveira DM, Mirante T, Camastra C, Gagliardi M, Rizzuto A, Mignogna C, Paciello O, Papparella S, Fagman H, Viglietto G. Malanga D, et al. Among authors: colelli f. PLoS One. 2016 Feb 9;11(2):e0147334. doi: 10.1371/journal.pone.0147334. eCollection 2016. PLoS One. 2016. PMID: 26859676 Free PMC article.