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Tendon response to matrix unloading is determined by the patho-physiological niche.
Wunderli SL, Blache U, Beretta Piccoli A, Niederöst B, Holenstein CN, Passini FS, Silván U, Bundgaard L, Auf dem Keller U, Snedeker JG. Wunderli SL, et al. Among authors: passini fs. Matrix Biol. 2020 Jul;89:11-26. doi: 10.1016/j.matbio.2019.12.003. Epub 2020 Jan 7. Matrix Biol. 2020. PMID: 31917255 Free article.
Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans.
Passini FS, Jaeger PK, Saab AS, Hanlon S, Chittim NA, Arlt MJ, Ferrari KD, Haenni D, Caprara S, Bollhalder M, Niederöst B, Horvath AN, Götschi T, Ma S, Passini-Tall B, Fucentese SF, Blache U, Silván U, Weber B, Silbernagel KG, Snedeker JG. Passini FS, et al. Nat Biomed Eng. 2021 Dec;5(12):1457-1471. doi: 10.1038/s41551-021-00716-x. Epub 2021 May 24. Nat Biomed Eng. 2021. PMID: 34031557 Free PMC article.
Load-induced regulation of tendon homeostasis by SPARC, a genetic predisposition factor for tendon and ligament injuries.
Wang T, Wagner A, Gehwolf R, Yan W, Passini FS, Thien C, Weissenbacher N, Lin Z, Lehner C, Teng H, Wittner C, Zheng Q, Dai J, Ni M, Wang A, Papadimitriou J, Leys T, Tuan RS, Senck S, Snedeker JG, Tempfer H, Jiang Q, Zheng MH, Traweger A. Wang T, et al. Among authors: passini fs. Sci Transl Med. 2021 Feb 24;13(582):eabe5738. doi: 10.1126/scitranslmed.abe5738. Sci Transl Med. 2021. PMID: 33627488