The model area is the northern surrounding of the water reservoir Zemplinska Irava in the east of Slovakia. Selection of the examined territory and the time horizons was not random. The aim was to capture the intensity level of anthropogenic impact on the values of the coefficient of ecological stability after the construction of water reservoir, Zempifnska Irava. The contribution evaluates ecological stability of landscape in the years 1956 and 2009 by GIS technology, using two methods. The first method determines the rate of ecological stability of landscape on the basis of the significance of land cover classes in the regular network of squares (the real size of the square is 0.5 square km). The second method determines the ecological stability of landscape secondary on the basis of the man influence on the landscape. A comparison of two methods has been made, as well as interpretation of the output data (e.g., monitoring the impact of marginal land cover classes with the minimal surfaces in the grid of square at the fluctuation of the index of ecological stability, respectively, it considers the possibilities to streamline the research results using homogeneous spatial units) and it also allows to track the changes in the ecological stability of the landscape in chronological development.