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Page 1
Showing results for smir males
Search for Esmir Maslesa instead (1 results)
Microglia induce the transformation of A1/A2 reactive astrocytes via the CXCR7/PI3K/Akt pathway in chronic post-surgical pain.
Li T, Liu T, Chen X, Li L, Feng M, Zhang Y, Wan L, Zhang C, Yao W. Li T, et al. J Neuroinflammation. 2020 Jul 14;17(1):211. doi: 10.1186/s12974-020-01891-5. J Neuroinflammation. 2020. PMID: 32665021 Free PMC article.
Intrathecal injection of minocycline relieved SMIR-induced mechanical allodynia and reverted the ratio of A1/A2 reactive astrocytes. The expression of CXCR7 and PI3K/Akt signaling was decreased after SMIR, while they were increased after treatment with minocycline. …
Intrathecal injection of minocycline relieved SMIR-induced mechanical allodynia and reverted the ratio of A1/A2 reactive astrocytes. …
Up-Regulation of CX3CL1 via STAT3 Contributes to SMIR-Induced Chronic Postsurgical Pain.
Shen Y, Li D, Li B, Xi P, Zhang Y, Jiang Y, Xu Y, Chen H, Xiong Y. Shen Y, et al. Neurochem Res. 2018 Mar;43(3):556-565. doi: 10.1007/s11064-017-2449-8. Epub 2018 Jan 8. Neurochem Res. 2018. PMID: 29313211
However, the underlying mechanism of CPSP remains unknown. Here, we used a skin/muscle incision and retraction (SMIR) model to investigate the role of CX3CL1 in SMIR-induced pain and its underlying mechanism. ...We also found that phospho-STAT3 co-localizes with CX3 …
However, the underlying mechanism of CPSP remains unknown. Here, we used a skin/muscle incision and retraction (SMIR) model to invest …
Retinal microvasculature alteration in central serous chorioretinopathy.
Yu L, Shao Y, Chai Y, Ye LH, Yang QC, Ye L, Yuan Q, Jiang N, Yi JL. Yu L, et al. Mol Med Rep. 2018 Feb;17(2):2335-2340. doi: 10.3892/mmr.2017.8126. Epub 2017 Nov 21. Mol Med Rep. 2018. PMID: 29207100 Free PMC article.
We found no significant difference in the density of SMIR with the quadrant partition method, whereas the annular partition method showed significantly decreased SMIR density only in the C1 region in patients with CSCR (P<0.05), with no significant difference obs …
We found no significant difference in the density of SMIR with the quadrant partition method, whereas the annular partition method sh …
Role of magnesium-L-Threonate in alleviating skin/muscle incision and retraction induced mechanical allodynia and anxiodepressive-like behaviors in male rats.
Chen Y, Zhang Y, Lin W, Tang Y, Chen L, Gao Y, Gao G, Luo X, Chen A, Lin C. Chen Y, et al. Brain Res. 2023 Oct 15;1817:148476. doi: 10.1016/j.brainres.2023.148476. Epub 2023 Jul 3. Brain Res. 2023. PMID: 37406874
In the SMIR model, rats developed mechanical allodynia and anxiodepressive-like behaviors. ...Repeated oral administration of L-TAMS increased serum and CSF levels of Mg(2+) in SMIR-injured rats. Notably, L-TAMS administration reversed SMIR-induced mechanical …
In the SMIR model, rats developed mechanical allodynia and anxiodepressive-like behaviors. ...Repeated oral administration of L-TAMS …
[Effects of intrathecal injection of IRF8 SiRNA on pain threshold and activation of spinal cord microglia in rats with postoperative persistent pain].
Xu CS, Lin C, Cai ZY. Xu CS, et al. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2022 Mar;38(2):113-118. doi: 10.12047/j.cjap.6220.2022.023. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2022. PMID: 36031567 Free article. Chinese.
Objective: To investigate the effects of intrathecal injection of IRF8 SiRNA on the pain threshold and activation of spinal cord microglia in rats with postoperative persistent pain. Methods: One hundred and twenty male Sprague-Dawley rats were randomly divided into sham g …
Objective: To investigate the effects of intrathecal injection of IRF8 SiRNA on the pain threshold and activation of spinal cord microglia i …
Effect of analgesic standards on persistent postoperative pain evoked by skin/muscle incision and retraction (SMIR).
Flatters SJ. Flatters SJ. Neurosci Lett. 2010 Jun 14;477(1):43-7. doi: 10.1016/j.neulet.2010.04.033. Epub 2010 Apr 24. Neurosci Lett. 2010. PMID: 20417687
Morphine (6mg/kg) and gabapentin (100mg/kg) elicited an almost complete reversal of SMIR-evoked mechanical hypersensitivity. In contrast, MK-801 (0.1mg/kg) did not affect SMIR-evoked mechanical hypersensitivity. ...As previously demonstrated, SMIR-evoked pain …
Morphine (6mg/kg) and gabapentin (100mg/kg) elicited an almost complete reversal of SMIR-evoked mechanical hypersensitivity. In contr …
The role of P2X7R/ERK signaling in dorsal root ganglia satellite glial cells in the development of chronic postsurgical pain induced by skin/muscle incision and retraction (SMIR).
Song J, Ying Y, Wang W, Liu X, Xu X, Wei X, Ruan X. Song J, et al. Brain Behav Immun. 2018 Mar;69:180-189. doi: 10.1016/j.bbi.2017.11.011. Epub 2017 Nov 17. Brain Behav Immun. 2018. PMID: 29155323
Intrathecal injection of ERK specific inhibitor SCH772984 suppressed the mechanical allodynia induced by SMIR. Furthermore, SMIR upregulated tumor necrosis factor alpha (TNFalpha) in L3 DRG, which could be inhibited by SCH772984. Intrathecal injection of TNF antagon …
Intrathecal injection of ERK specific inhibitor SCH772984 suppressed the mechanical allodynia induced by SMIR. Furthermore, SMIR …
Diversification of the insulin receptor family in the helminth parasite Schistosoma mansoni.
Khayath N, Vicogne J, Ahier A, BenYounes A, Konrad C, Trolet J, Viscogliosi E, Brehm K, Dissous C. Khayath N, et al. FEBS J. 2007 Feb;274(3):659-76. doi: 10.1111/j.1742-4658.2006.05610.x. Epub 2006 Dec 20. FEBS J. 2007. PMID: 17181541 Free article.
This work demonstrates the existence of two distinct IR homologs (SmIR-1 and SmIR-2) in the parasite trematode Schistosoma mansoni. ...SmIR-1 and SmIR-2 were shown to interact with human pro-insulin but not with pro-insulin-like growth factor-1 in two- …
This work demonstrates the existence of two distinct IR homologs (SmIR-1 and SmIR-2) in the parasite trematode Schistosoma man …
Skin/Muscle Incision and Retraction Induces Evoked and Spontaneous Pain in Mice.
Yang J, Yuan F, Ye G, Wang YJ, Wu C, Wang J, Li XY, Feng Z. Yang J, et al. Pain Res Manag. 2019 Jul 31;2019:6528528. doi: 10.1155/2019/6528528. eCollection 2019. Pain Res Manag. 2019. PMID: 31467625 Free PMC article.
However, the mice model of SMIR did not evoke significant heat hypersensitivity. Systemic injection of clonidine and gabapentin raised the PWT in the SMIR mice dose-dependently. ...However, clonidine but not gabapentin could alleviate the spontaneous pain of SMIR …
However, the mice model of SMIR did not evoke significant heat hypersensitivity. Systemic injection of clonidine and gabapentin raise …
The different mechanisms of peripheral and central TLR4 on chronic postsurgical pain in rats.
Han X, Shao J, Ren X, Li Y, Yu W, Lin C, Li L, Sun Y, Xu B, Luo H, Zhu C, Cao J, Li Z. Han X, et al. J Anat. 2021 Jul;239(1):111-124. doi: 10.1111/joa.13406. Epub 2021 Mar 17. J Anat. 2021. PMID: 33730389 Free PMC article.
In the present study, we established a rat model of CPSP induced by skin/muscle incision and retraction (SMIR) and verified the effects and mechanisms of central and peripheral TLR4 and NF-kappaB on hyperalgesia in SMIR rats. ...In the central nervous system, the TL …
In the present study, we established a rat model of CPSP induced by skin/muscle incision and retraction (SMIR) and verified the effec …
63 results