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The following term was not found in PubMed: Macharm
Page 1
The growing relevance of biological ene reactions.
Jensen AW, Mohanty DK, Dilling WL. Jensen AW, et al. Bioorg Med Chem. 2019 Mar 1;27(5):686-691. doi: 10.1016/j.bmc.2019.01.020. Epub 2019 Jan 24. Bioorg Med Chem. 2019. PMID: 30709643 Review.
The ene reaction involves the addition of an 'ene' to an 'enophile.' The retro-ene reaction is the reverse of the ene reaction. In recent years various biological molecules have been found to form covalent intermediates (ene-adducts) that might …
The ene reaction involves the addition of an 'ene' to an 'enophile.' The retro-ene reaction is the reverse of the en …
Palladium-Catalyzed Intramolecular Alder-Ene Type Cycloisomerization Reactions.
Yadav S, Ramasastry SSV. Yadav S, et al. Chem Asian J. 2020 Sep 15;15(18):2764-2774. doi: 10.1002/asia.202000683. Epub 2020 Aug 7. Chem Asian J. 2020. PMID: 32667724 Review.
An overview of the recent literature on palladium-catalyzed intramolecular Alder-ene (IMAE) reaction of a variety of 1,n-unsaturated systems is presented. The reaction which was first reported by Trost and Lautens provided an efficient alternative to the thermal or Lewis a …
An overview of the recent literature on palladium-catalyzed intramolecular Alder-ene (IMAE) reaction of a variety of 1,n-unsaturated …
Ene cyclization reaction in heterocycle synthesis.
Saha P, Saikia AK. Saha P, et al. Org Biomol Chem. 2018 Apr 25;16(16):2820-2840. doi: 10.1039/c8ob00429c. Org Biomol Chem. 2018. PMID: 29594296 Review.
The ene cyclization has evolved to become an indispensable tool for the synthesis of various ring size heterocyclic compounds. ...Moreover, the ease of regio- and stereoselectivity of ene cyclization has led to the development of new types of heterocyclic compounds. …
The ene cyclization has evolved to become an indispensable tool for the synthesis of various ring size heterocyclic compounds. ...Mor …
Applications of Thiol-Ene Chemistry for Peptide Science.
Nolan MD, Scanlan EM. Nolan MD, et al. Front Chem. 2020 Nov 12;8:583272. doi: 10.3389/fchem.2020.583272. eCollection 2020. Front Chem. 2020. PMID: 33282831 Free PMC article. Review.
The thiol-ene reaction offers a number of advantages in this area, primarily those characteristic of "click" reactions. ...This review will cover the range of applications of the radical-mediated thiol-ene reaction in peptide and protein science....
The thiol-ene reaction offers a number of advantages in this area, primarily those characteristic of "click" reactions. ...This revie …
5-Ene-4-thiazolidinones - An efficient tool in medicinal chemistry.
Kaminskyy D, Kryshchyshyn A, Lesyk R. Kaminskyy D, et al. Eur J Med Chem. 2017 Nov 10;140:542-594. doi: 10.1016/j.ejmech.2017.09.031. Epub 2017 Sep 20. Eur J Med Chem. 2017. PMID: 28987611 Free PMC article. Review.
Nevertheless, the crucial impact of the presence/nature of C5 substituent (namely 5-ene) on the pharmacological effects of 5-ene-4-thiazolidinones was confirmed by the numerous listed findings from the original articles. ...Moreover, the utilization of 5-ene- …
Nevertheless, the crucial impact of the presence/nature of C5 substituent (namely 5-ene) on the pharmacological effects of 5-ene …
The aromatic ene reaction.
Niu D, Hoye TR. Niu D, et al. Nat Chem. 2014 Jan;6(1):34-40. doi: 10.1038/nchem.1797. Epub 2013 Nov 17. Nat Chem. 2014. PMID: 24345944 Free PMC article.
The ene reaction is a pericyclic process in which an alkene with an allylic hydrogen atom (the ene donor) reacts with a second unsaturated species (the enophile) to form a new product with a transposed pi-bond. ...Our experiments were guided by computational studies …
The ene reaction is a pericyclic process in which an alkene with an allylic hydrogen atom (the ene donor) reacts with a second …
Asymmetric Ene-Reduction by F(420) -Dependent Oxidoreductases B (FDOR-B) from Mycobacterium smegmatis.
Kang SW, Antoney J, Lupton DW, Speight R, Scott C, Jackson CJ. Kang SW, et al. Chembiochem. 2023 Apr 17;24(8):e202200797. doi: 10.1002/cbic.202200797. Epub 2023 Mar 8. Chembiochem. 2023. PMID: 36716144
Asymmetric reduction by ene-reductases has received considerable attention in recent decades. While several enzyme families possess ene-reductase activity, the Old Yellow Enzyme (OYE) family has received the most scientific and industrial attention. ...
Asymmetric reduction by ene-reductases has received considerable attention in recent decades. While several enzyme families possess …
Tunable and Magnetic Thiol-ene Micropillar Arrays.
Al-Azawi A, Cenev Z, Tupasela T, Peng B, Ikkala O, Zhou Q, Jokinen V, Franssila S, Ras RHA. Al-Azawi A, et al. Macromol Rapid Commun. 2020 Jan;41(2):e1900522. doi: 10.1002/marc.201900522. Epub 2019 Nov 28. Macromol Rapid Commun. 2020. PMID: 31778287
Inspired by cilia structure in the respiratory pathway, magnetically responsive periodic arrays of flexible and magnetic thiol-ene micropillars are fabricated. Omnidirectional collective bending of the pillar array in magnetic field is shown. Local non-contact actuation of …
Inspired by cilia structure in the respiratory pathway, magnetically responsive periodic arrays of flexible and magnetic thiol-ene mi …
Thermal, electrochemical and photochemical reactions involving catalytically versatile ene reductase enzymes.
Toogood HS, Scrutton NS. Toogood HS, et al. Enzymes. 2020;47:491-515. doi: 10.1016/bs.enz.2020.05.012. Epub 2020 Jul 18. Enzymes. 2020. PMID: 32951833 Review.
This review will outline current progress in the design of alternative routes to ene reductase flavin activation, most notably within the Old Yellow Enzyme family. ...Photochemical approaches have also enabled novel mechanistic routes of ene reductases to become ava …
This review will outline current progress in the design of alternative routes to ene reductase flavin activation, most notably within …
The "How" and "Where" Behind the Functionalization of Graphene Oxide by Thiol-ene "Click" Chemistry.
Piñeiro-García A, Semetey V. Piñeiro-García A, et al. Chemistry. 2023 Sep 6;29(50):e202301604. doi: 10.1002/chem.202301604. Epub 2023 Aug 7. Chemistry. 2023. PMID: 37367388 Review.
However, traditional strategies that employ epoxides, alcohols, and carboxylic acids suffer from low control and undesirable side reactions, including by-product formation and GO reduction. Thiol-ene "click" reaction offers a promising and versatile chemical approach for t …
However, traditional strategies that employ epoxides, alcohols, and carboxylic acids suffer from low control and undesirable side reactions, …
15,706 results
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