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Year | Number of Results |
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2019 | 1 |
2021 | 1 |
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2023 | 3 |
2024 | 0 |
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Page 1
Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Sci Adv. 2023 Mar 29;9(13):eade8778. doi: 10.1126/sciadv.ade8778. Epub 2023 Mar 29.
Sci Adv. 2023.
PMID: 36989354
Free PMC article.
SARS-CoV-2 3CLpro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376.
Heilmann E, Costacurta F, Moghadasi SA, Ye C, Pavan M, Bassani D, Volland A, Ascher C, Weiss AKH, Bante D, Harris RS, Moro S, Rupp B, Martinez-Sobrido L, von Laer D.
Heilmann E, et al.
Sci Transl Med. 2023 Jan 11;15(678):eabq7360. doi: 10.1126/scitranslmed.abq7360. Epub 2023 Jan 11.
Sci Transl Med. 2023.
PMID: 36194133
Free PMC article.
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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Sprenger B, Moghadasi SA, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Kaserer T, Moro S, von Laer D, Heilmann E.
Costacurta F, et al. Among authors: heilmann e.
bioRxiv [Preprint]. 2023 Oct 4:2023.09.22.558628. doi: 10.1101/2023.09.22.558628.
bioRxiv. 2023.
PMID: 37808638
Free PMC article.
Preprint.
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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Moghadasi SA, Heilmann E, Khalil AM, Nnabuife C, Kearns FL, Ye C, Moraes SN, Costacurta F, Esler MA, Aihara H, von Laer D, Martinez-Sobrido L, Palzkill T, Amaro RE, Harris RS.
Moghadasi SA, et al. Among authors: heilmann e.
bioRxiv [Preprint]. 2022 Dec 26:2022.08.07.503099. doi: 10.1101/2022.08.07.503099.
bioRxiv. 2022.
PMID: 35982678
Free PMC article.
Updated.
Preprint.
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A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition.
Heilmann E, Costacurta F, Geley S, Mogadashi SA, Volland A, Rupp B, Harris RS, von Laer D.
Heilmann E, et al.
Commun Biol. 2022 Apr 27;5(1):391. doi: 10.1038/s42003-022-03277-0.
Commun Biol. 2022.
PMID: 35478219
Free PMC article.
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Heparan sulfate proteoglycans serve as alternative receptors for low affinity LCMV variants.
Volland A, Lohmüller M, Heilmann E, Kimpel J, Herzog S, von Laer D.
Volland A, et al. Among authors: heilmann e.
PLoS Pathog. 2021 Oct 14;17(10):e1009996. doi: 10.1371/journal.ppat.1009996. eCollection 2021 Oct.
PLoS Pathog. 2021.
PMID: 34648606
Free PMC article.
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The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion.
Heilmann E, Kimpel J, Geley S, Naschberger A, Urbiola C, Nolden T, von Laer D, Wollmann G.
Heilmann E, et al.
Viruses. 2019 Oct 26;11(11):989. doi: 10.3390/v11110989.
Viruses. 2019.
PMID: 31717818
Free PMC article.
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