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Page 1
Targeting the substrate preference of a type I nitroreductase to develop antitrypanosomal quinone-based prodrugs.
Antimicrob Agents Chemother. 2012 Nov;56(11):5821-30. doi: 10.1128/AAC.01227-12. Epub 2012 Sep 4.
Antimicrob Agents Chemother. 2012.
PMID: 22948871
Free PMC article.
Unravelling the role of SNM1 in the DNA repair system of Trypanosoma brucei.
Sullivan JA, Tong JL, Wong M, Kumar A, Sarkar H, Ali S, Hussein I, Zaman I, Meredith EL, Helsby NA, Hu L, Wilkinson SR.
Sullivan JA, et al. Among authors: meredith el.
Mol Microbiol. 2015 May;96(4):827-38. doi: 10.1111/mmi.12973. Epub 2015 Mar 21.
Mol Microbiol. 2015.
PMID: 25689597
Free article.
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Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs.
Meredith EL, Kumar A, Konno A, Szular J, Alsford S, Seifert K, Horn D, Wilkinson SR.
Meredith EL, et al.
Mol Microbiol. 2017 Oct;106(2):207-222. doi: 10.1111/mmi.13767. Epub 2017 Aug 31.
Mol Microbiol. 2017.
PMID: 28792090
Free PMC article.
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