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The following term was not found in PubMed: Elvedin
Page 1
Halimanes and cancer: ent-halimic acid as a starting material for the synthesis of antitumor drugs.
Roncero AM, Tobal IE, Moro RF, Diez D, Marcos IS. Roncero AM, et al. Front Chem. 2023 Aug 22;11:1225355. doi: 10.3389/fchem.2023.1225355. eCollection 2023. Front Chem. 2023. PMID: 37674527 Free PMC article. Review.
Many of them exhibit biological activities such as antitumor, antimicrobial, or anti-inflammatory. Among them, ent-halimic acid is an easily accessible compound, in large quantities, from the ethyl acetate extract of the plant Halimium viscosum, and it has been used as a s …
Many of them exhibit biological activities such as antitumor, antimicrobial, or anti-inflammatory. Among them, ent-halimic acid is an …
The Methylene-Cycloalkylacetate (MCA) Scaffold in Terpenyl Compounds with Potential Pharmacological Activities.
Tobal IE, Roncero AM, Moro RF, Díez D, Marcos IS. Tobal IE, et al. Molecules. 2019 Jun 5;24(11):2120. doi: 10.3390/molecules24112120. Molecules. 2019. PMID: 31195609 Free PMC article. Review.
In this work, natural diterpenes that embed MCA fragments are reviewed, as they are major components of Halimium viscosum: ent-halimic acid, the prototype for these bioactive compounds. Herein, structures, sources, and activities for the natural diterpenes, as well as thei …
In this work, natural diterpenes that embed MCA fragments are reviewed, as they are major components of Halimium viscosum: ent-halimic …
Synthesis of an ent-halimanolide from ent-halimic acid.
Marcos IS, Conde A, Moro RF, Basabe P, Díez D, Mollinedo F, Urones JG. Marcos IS, et al. Molecules. 2008 May 9;13(5):1120-34. doi: 10.3390/molecules13051120. Molecules. 2008. PMID: 18560332 Free PMC article.
An efficient synthesis of ent-halimanolide 2 (15,16-epoxy-12-oxo-ent-halima- 5(10),13(16),14-trien-18,2beta-olide), from ent-halimic acid has been achieved, corroborating the structure of the natural compound and establishing its absolute configuration....
An efficient synthesis of ent-halimanolide 2 (15,16-epoxy-12-oxo-ent-halima- 5(10),13(16),14-trien-18,2beta-olide), from ent-halimic …
Synthesis and biological activity of polyalthenol and pentacyclindole analogues.
Marcos IS, Moro RF, Costales I, Basabe P, Díez D, Gil A, Mollinedo F, Pérez-de la Rosa F, Pérez-Roth E, Padrón JM. Marcos IS, et al. Eur J Med Chem. 2014 Feb 12;73:265-79. doi: 10.1016/j.ejmech.2013.12.012. Epub 2013 Dec 25. Eur J Med Chem. 2014. PMID: 24412720
A series of indole sesquiterpenes analogues of polyalthenol and pentacyclindole have been synthesized starting from ent-halimic acid in order to test their biological activity. These analogues include diverse oxidation levels at the sesquiterpenyl moiety and different func …
A series of indole sesquiterpenes analogues of polyalthenol and pentacyclindole have been synthesized starting from ent-halimic acid …
Synthesis of bioactive sesterterpenolides from ent-halimic acid. 15-epi-ent-Cladocoran A and B.
Marcos IS, Pedrero AB, Sexmero MJ, Diez D, Basabe P, García N, Moro RF, Broughton HB, Mollinedo F, Urones JG. Marcos IS, et al. J Org Chem. 2003 Sep 19;68(19):7496-504. doi: 10.1021/jo034663l. J Org Chem. 2003. PMID: 12968906
The bioactive sesterterpenoid gamma-hydroxybutenolides 15,18-bisepi-ent-Cladocoran A and B, 1 and 2, and 15-epi-ent-Cladocoran A and B, 57 and 55, were synthesized from ent-halimic acid. The synthesized sesterterpenolids 2, 55, 57, and 59 inhibited cellular proliferation ( …
The bioactive sesterterpenoid gamma-hydroxybutenolides 15,18-bisepi-ent-Cladocoran A and B, 1 and 2, and 15-epi-ent-Cladocoran A and B, 57 a …
Synthetic studies towards the ent-labdane diterpenoids: rearrangement of ent-halimanes.
Marcos IS, Sexmero MJ, Hernández FA, Corrales M, Basabe P, Díez D, Urones JG. Marcos IS, et al. Molecules. 2006 Oct 24;11(10):792-807. doi: 10.3390/11100792. Molecules. 2006. PMID: 17971756 Free PMC article.
For the first time ent-labdanes have been synthetised starting from ent-halimic acid, following a route that is the reverse of the biosynthetic one leading to the former compounds....
For the first time ent-labdanes have been synthetised starting from ent-halimic acid, following a route that is the reverse of the bi …
25 results