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Page 1
State-matched organoid models to fight pancreatic cancer.
Melzer MK, Roger E, Kleger A. Melzer MK, et al. Among authors: roger e. Trends Cancer. 2022 Jun;8(6):445-447. doi: 10.1016/j.trecan.2022.03.003. Epub 2022 Mar 31. Trends Cancer. 2022. PMID: 35370114
Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer.
Gout J, Perkhofer L, Morawe M, Arnold F, Ihle M, Biber S, Lange S, Roger E, Kraus JM, Stifter K, Hahn SA, Zamperone A, Engleitner T, Müller M, Walter K, Rodriguez-Aznar E, Sainz B Jr, Hermann PC, Hessmann E, Müller S, Azoitei N, Lechel A, Liebau S, Wagner M, Simeone DM, Kestler HA, Seufferlein T, Wiesmüller L, Rad R, Frappart PO, Kleger A. Gout J, et al. Among authors: roger e. Gut. 2021 Apr;70(4):743-760. doi: 10.1136/gutjnl-2019-319970. Epub 2020 Sep 1. Gut. 2021. PMID: 32873698 Free PMC article.
Organoids at the PUB: The Porcine Urinary Bladder Serves as a Pancreatic Niche for Advanced Cancer Modeling.
Melzer MK, Breunig M, Arnold F, Wezel F, Azoitei A, Roger E, Krüger J, Merkle J, Schütte L, Resheq Y, Hänle M, Zehe V, Zengerling F, Azoitei N, Klein L, Penz F, Singh SK, Seufferlein T, Hohwieler M, Bolenz C, Günes C, Gout J, Kleger A. Melzer MK, et al. Among authors: roger e. Adv Healthc Mater. 2022 Jun;11(11):e2102345. doi: 10.1002/adhm.202102345. Epub 2022 Feb 18. Adv Healthc Mater. 2022. PMID: 35114730
RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer.
Arnold F, Gout J, Wiese H, Weissinger SE, Roger E, Perkhofer L, Walter K, Scheible J, Prelli Bozzo C, Lechel A, Ettrich TJ, Azoitei N, Hao L, Fürstberger A, Kaminska EK, Sparrer KMJ, Rasche V, Wiese S, Kestler HA, Möller P, Seufferlein T, Frappart PO, Kleger A. Arnold F, et al. Among authors: roger e. Cancer Res. 2021 Apr 1;81(7):1758-1774. doi: 10.1158/0008-5472.CAN-20-2633. Epub 2021 Feb 2. Cancer Res. 2021. PMID: 33531371
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration.
Arnold F, Mahaddalkar PU, Kraus JM, Zhong X, Bergmann W, Srinivasan D, Gout J, Roger E, Beutel AK, Zizer E, Tharehalli U, Daiss N, Russell R, Perkhofer L, Oellinger R, Lin Q, Azoitei N, Weiss FU, Lerch MM, Liebau S, Katz SF, Lechel A, Rad R, Seufferlein T, Kestler HA, Ott M, Sharma AD, Hermann PC, Kleger A. Arnold F, et al. Among authors: roger e. Adv Sci (Weinh). 2021 May 13;8(14):2100626. doi: 10.1002/advs.202100626. eCollection 2021 Jul. Adv Sci (Weinh). 2021. PMID: 34306986 Free PMC article.
Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling.
Roger E, Martel S, Bertrand-Chapel A, Depollier A, Chuvin N, Pommier RM, Yacoub K, Caligaris C, Cardot-Ruffino V, Chauvet V, Aires S, Mohkam K, Mabrut JY, Adham M, Fenouil T, Hervieu V, Broutier L, Castets M, Neuzillet C, Cassier PA, Tomasini R, Sentis S, Bartholin L. Roger E, et al. Cell Death Dis. 2019 Nov 25;10(12):886. doi: 10.1038/s41419-019-2116-x. Cell Death Dis. 2019. PMID: 31767842 Free PMC article.
A Prospective Feasibility Trial to Challenge Patient-Derived Pancreatic Cancer Organoids in Predicting Treatment Response.
Beutel AK, Schütte L, Scheible J, Roger E, Müller M, Perkhofer L, Kestler AMTU, Kraus JM, Kestler HA, Barth TFE, Lemke J, Kornmann M, Ettrich TJ, Gout J, Seufferlein T, Kleger A. Beutel AK, et al. Among authors: roger e. Cancers (Basel). 2021 May 21;13(11):2539. doi: 10.3390/cancers13112539. Cancers (Basel). 2021. PMID: 34064221 Free PMC article.
12 results